Protective Effects of Ethanolic Extract of Ageratum conyzoides on Experimental Induced Inflammatory Bowel Disease

Biradar, Siddaruda M; Aswathanar, B.J.; Kulkarni, V. H.; �Kulkarni, Preeti; Smita, D. M.; Tarak, K.C.

doi:10.3923/jpt.2011.664.678

Cited by 5 publications

(4 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A. conyzoides pretreatment has protective and regeneration effects on colonic cells, according to a histopathological report. The finding of this study provides evidence that ethanolic extract of A. conyzoides may be beneficial in patients suffering from inflammatory bowel disease (Biradar et al, 2011).…”

Section: Anti-inflammatory Propertymentioning

confidence: 56%

“…As compared to the disease-inducing population, pretreatment with ethanolic extract of A.conyzoides at doses of 500 and 750 mg kg -1 , p.o. (per oral) and a standard group of animals showed significant attenuated results in all of the studied parameters which included macroscopic evaluation (scoring of ulcers), microscopic evaluation (histopathology), estimation of biochemical parameters (myeloperoxidase and lipid peroxides) and measurement of physical parameters (change in body weight and colon weight) (Biradar et al, 2011). A. conyzoides pretreatment has protective and regeneration effects on colonic cells, according to a histopathological report.…”

Section: Anti-inflammatory Propertymentioning

confidence: 91%

See 1 more Smart Citation

Ageratum conyzoides: A Potential Source for Medicinal and Agricultural Products

Baral

Chaudhary

Lamichhane

et al. 2022

Turkish JAF Sci.Tech.

View full text Add to dashboard Cite

Ageratum conyzoides is a widely spread weed, especially in the tropical and subtropical regions. It has been reported to be used as folk medicine in different countries for treating burns, wounds, skin disorders, headaches, fever, pneumonia, gynecological diseases, leprosy, snakebites, rheumatism, inflammations, stomach ailments like parasites, colic, diarrhea, dysentery, used as a painkiller during childbirth, and many more. It has been reported to contain active secondary metabolites such as alkaloids, tannins, phenols, saponins, coumarins, essential oils, and flavonoids, which support its medicinal uses in disease treatment and prevention. It can be a potential source of drugs for various diseases. In fact, pharmaceutical companies are being run in Brazil using A. conyzoides as raw material with recommendations from the Brazilian Drug Centre. It is also used for agricultural purposes as manure, insecticide, pesticide, herbicide, nematicide, fodder, etc. In China, it is widely intercropped in the citrus orchard to control pests and weeds. The review attempts to bring together medicinal and agricultural usage of Ageratum conyzoides with scientific evidence to demonstrate its efficacy. This weed has a negative influence in agriculture and the ecosystem but after studying about its potential medical and agricultural uses, we now have a different viewpoint on this weed, and we believe that further harnessing it for such positive uses might be a management strategy for this weed.

show abstract

Section: Anti-inflammatory Propertymentioning

confidence: 56%

Section: Anti-inflammatory Propertymentioning

confidence: 91%

Ageratum conyzoides: A Potential Source for Medicinal and Agricultural Products

Baral

Chaudhary

Lamichhane

et al. 2022

Turkish JAF Sci.Tech.

View full text Add to dashboard Cite

show abstract

“…These studies have demonstrated that A. conyzoides L. has several pharmacological properties, including analgesic (Yamamoto et al, 1991), antimicrobial (Adetutu et al, 2012;Durodola, 1977), antiprotozoal (Harel et al, 2011;Nour et al, 2010;Ukwe et al, 2010), anti-cancer and radical scavenging and antiinflammatory actions (Biradar et al, 2011;Hassan et al, 2012;Moura et al, 2005). The active components of this herb may provide a useful platform for the development of effective pharmacological agents with potent anti-inflammatory properties.…”

Section: Introductionmentioning

confidence: 95%

Beneficial effect of Ageratum conyzoides Linn (Asteraceae) upon inflammatory response induced by carrageenan into the mice pleural cavity

Mello

Rosa

Facchin

et al. 2016

Journal of Ethnopharmacology

View full text Add to dashboard Cite

“…Crohn's disease (an inflammatory bowel disease -IBD) is a chronic gastrointestinal inflammatory disorder (1)(2)(3)(4)(5)(6)(7)(8)(9). Although it is a widespread disease, its etiology and mechanism are still not properly understood (2).…”

Section: Introductionmentioning

confidence: 99%

An Integrated Traditional Therapy Approach Involving Yagya Therapy In Patient With Symptoms Similar to Crohn's Disease

Shrivastava¹,

Batham²,

Mishra³

et al. 2019

Interdis. J of Yagya Res.

View full text Add to dashboard Cite

Background: Crohn’s disease (an inflammatory bowel disease - IBD) is a chronic gastrointestinal inflammatory disorder. Common symptoms include rectal bleeding, persistent diarrhea, abdominal pain, extreme fatigue, weight loss, constipation, etc. Although it is a widespread disease, its etiology and mechanism are still not properly understood. Hence, even though several treatment methodologies have been employed for the management of the symptoms associated with the Crohn's disease - side-effect free, long-term management of this disease is still not achieved. Purpose: As per the classical texts of Ayurveda, Pachak Pitta, Saman Vayu and Kledak Kapha are responsible for proper digestion; vikriti (vitiation) of these Doshas can lead to various types of diseases of the gastrointestinal tract. Hence, herbal medicines that balance these Doshas, as well as provide nourishment to the body tissues, can be recommended for the management of the observed symptoms of the disease in the present study. Yagya Therapy provides pulmonary inhalation of medicinal smoke of multiple herbs (generated through oblation in fire along with chanting of Vedic hymns), which provide therapeutic benefits. The Vedic hymns also contribute to the positive restructuring of the psyche of the patient. Methodology: A case report about a male patient, who was suffering from symptoms similar to those found in Crohn's disease, has been presented in this article. The patient was prescribed an integrated approach pivoting on Yagya Therapy (using an appropriate herbal formulation - hawan-samagri), and some other Ayurvedic treatments like decoction of medicinal herbs, dietary restrictions, etc. Results: Before starting the integrated approach involving Yagya Therapy , the patient used to have severe pain in the abdomen, had swelling and stiffness in legs, had constipation, as well as weight loss; after taking the integrated approach involving Yagya Therapy , there was significant relief in the pain, the swelling in the legs was completely resolved, the stiffness in the legs had reduced, constipation was significantly reduced, as well as there was slight increase in weight. Earlier, because of weakness, the patient had difficulty in walking, changing posture from sitting to standing and vice versa, changing side while lying down; after taking the integrated approach, the patient feels an enhanced strength in his legs, has started walking on his own, can change posture from sitting to standing and vice versa on his own, can change side while lying down on his own. Overall, there was definite improvement in the condition of the patient. Conclusion: The integrated approach involving Yagya Therapy showed encouraging results with respect to the management of symptoms similar to those found in Crohn's disease.

show abstract

Protective Effects of Ethanolic Extract of Ageratum conyzoides on Experimental Induced Inflammatory Bowel Disease

Cited by 5 publications

References 16 publications

Ageratum conyzoides: A Potential Source for Medicinal and Agricultural Products

Ageratum conyzoides: A Potential Source for Medicinal and Agricultural Products

Beneficial effect of Ageratum conyzoides Linn (Asteraceae) upon inflammatory response induced by carrageenan into the mice pleural cavity

An Integrated Traditional Therapy Approach Involving Yagya Therapy In Patient With Symptoms Similar to Crohn's Disease

Contact Info

Product

Resources

About