Protective effects of cranberries on infection-induced oxidative renal damage in a rabbit model of vesico-ureteric reflux

Han, Chun-Mei; Sh, Kim; Kang, SH; Or, Shin; Lee, Hyun Kyung; Kim, Hyung Jun; Yh, Cho

doi:10.1590/s1677-55382007000600033

Cited by 3 publications

(7 citation statements)

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“…(2007) supplemented healthy women with dried cranberry juice (400 mg/day) for 8 weeks and again, no effect was seen on markers of oxidative stress (superoxide dismutase, glutathione, and glutathione peroxidase). However, the results of these studies are in contrast to those from another study done in rabbits suffering from infection‐induced oxidative renal damage, where supplementation with cranberry powder (1 g/kg bwt/day) for 3 weeks resulted in a significant reduction in malonedialdehyde (MDA), an indicator of oxidative stress (Han et al . 2007).…”

Section: Discussionmentioning

confidence: 62%

“…2009). A recent study in male New Zealand rabbit kidneys shows that cranberry powder decreases both accumulation of malonedialdehyde (MDA, an indicator of oxidative damage) and inflammation when challenged with an infection of Escherichia coli (Han et al . 2007).…”

Section: Introductionmentioning

confidence: 99%

“…Anthocyanins, flavonoids that cause the red colour found in cranberries, are also powerful antioxidants (Viskelis et al 2009). A recent study in male New Zealand rabbit kidneys shows that cranberry powder decreases both accumulation of malonedialdehyde (MDA, an indicator of oxidative damage) and inflammation when challenged with an infection of Escherichia coli (Han et al 2007). Based on these studies showing antioxidant properties of cranberries, administration with cranberry extract could aid in increasing the antioxidant status of exercising horses.…”

Section: Introductionmentioning

confidence: 99%

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Oxidative stress and antioxidant status in intensely exercising horses administered nutraceutical extracts

Smarsh

Liburt

Streltsova

et al. 2010

Equine Veterinary Journal

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SummaryReasons for performing study: Many nutraceuticals are used as equine supplements without their efficacy having been scientifically tested. Black tea, cranberries, orange peel and ginger are a few of those nutraceuticals that warrant further study. Objective: To test the effects of single doses of black tea, cranberry, orange peel and ginger extract on markers of oxidative stress and antioxidant status following exercise in horses. Methods: In Study 1, 9 mature, healthy but unfit Standardbred mares were administered 2 l of a control (water), orange peel extract (30 g extract) or decaffeinated black tea extract (28 g extract). In Study 2 the same mares were administered 2 l of a control (water), cranberry extract (30 g extract) or ginger extract (30 g extract). In each study, mares were given the extracts via nasogastric tube 1 h before performing a graded exercise test (GXT), in a randomised crossover design with at least 7 days between GXTs. Blood samples were collected at rest, at fatigue, and 1 and 24 h post exercise and analysed for lipid hydroperoxides (LPO), total glutathione (GSH-T), glutathione peroxidase (GPx), a-tocopherol (TOC), b-carotene (BC) and retinol. Data were statistically analysed using a repeated measures ANOVA. Results: In Study 1 there was no effect of treatment for LPO, GSH-T, GPx, TOC or BC. Retinol was higher for both tea (P = 0.0006) and water (P = 0.004) than for orange peel. In Study 2 there was no treatment effect for LPO, GPx, GSH-T, RET, BC or TOC. Conclusions:The results show that a single dose of various nutraceuticals in exercising horses do not produce an effect on either oxidative stress or antioxidant status and further investigation is needed as to whether long-term supplementation would enhance these effects.

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Section: Discussionmentioning

confidence: 62%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Oxidative stress and antioxidant status in intensely exercising horses administered nutraceutical extracts

Smarsh

Liburt

Streltsova

et al. 2010

Equine Veterinary Journal

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“…Recent randomized controlled trials demonstrate that cranberry juice has been shown to prevent bacteriuria in elderly people and UTI in women and it has been suggested as an alternative to antibiotic therapy for prevention of UTI 4 . The mechanisms for its beneficial effect were thought to involve urine acidification by an increase in hippuric acid secretion, 7 action by inhibiting the adhesion of Escherichia Coli , 8 and an anti‐inflammatory effect through their antioxidant function 9 . Theoretically, cranberry juice can provide a reduction of bacteriuria in the urine and may prevent the development of upper UTI if the pathogen is drug‐resistant bacteria.…”

Section: Discussionmentioning

confidence: 99%

Can cranberry juice be a substitute for cefaclor prophylaxis in children with vesicoureteral reflux?

Nishizaki

Someya

Hirano

et al. 2009

Pediatrics International

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“…Otro estudio, realizado en conejos, concluye que los arándanos pueden prevenir la pielonefritis, gracias a su efecto antioxidante y antinflamatorio que previene el daño a nivel renal (Han et al, 2007).…”

Section: Actividad Antiinflamatoriaunclassified

Efecto de los arándanos sobre el estado oxidativo de la leche en madres con mastitis

García¹

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A Hermelinda, gracias por tu absoluta disponibilidad, y por tu esfuerzo y trabajo en mis ausencias en la farmacia.A todas las madres que generosamente contribuyeron en este estudio con su participación. 12A mi amiga Sandra Brunori, gracias por la portada, has captado perfectamente la idea que yo llevaba, ¡¡¡me encanta!!! A mis amigas, María Segarra y Teresa García, porque sois la familia que se escoge, por vuestros ánimos, porque siempre estáis cuando os necesito, y habéis compartido conmigo todo este camino. Esta tesis ha dado para varios "Charquitos" y un viaje a París.A mi prima, la Dra. Marta Pilar Montañez por tu disposición, dedicación y trabajo para que esta tesis tomara forma. Si no hubiese sido por ti, aún estaría peleándome con las sangrías, los encabezados y los pies de página. Gracias por tus correcciones, por tus sabios consejos, cada segundo hablado contigo lo he aprovechado; y por acompañarme en la recta final de esta aventura.A mis hermanos Manuel y Catalina, por estar ahí siempre y cuidar de mis hijos cuando lo he necesitado.A mi hermana Teresa, con la que comparto profesión, gracias por haber supervisado mi trabajo, por saber escuchar, por tu generosidad y ayuda incondicionales en todos los momentos importantes de mi vida. Sabes que esta tesis lleva también tu nombre.A Mónica, mi amiga y compañera de vida, por animarme y apoyarme en todos mis proyectos, especialmente en este. Gracias por estar siempre a mi lado.A mis hijos Diego y Balma, porque con Diego descubrí la lactancia y con Balma la sigo disfrutando. Vosotros habéis sido el mejor motivo para terminarla.

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Protective effects of cranberries on infection-induced oxidative renal damage in a rabbit model of vesico-ureteric reflux

Cited by 3 publications

References 0 publications

Oxidative stress and antioxidant status in intensely exercising horses administered nutraceutical extracts

Oxidative stress and antioxidant status in intensely exercising horses administered nutraceutical extracts

Can cranberry juice be a substitute for cefaclor prophylaxis in children with vesicoureteral reflux?

Efecto de los arándanos sobre el estado oxidativo de la leche en madres con mastitis

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