Can cranberry juice be a substitute for cefaclor prophylaxis in children with vesicoureteral reflux?

Nishizaki, Naoto; Someya, Tomonosuke; Hirano, Daishi; Fujinaga, Shuichiro; Ohtomo, Yoshiyuki; Shimizu, Toshiaki; Kaneko, Kazunari

doi:10.1111/j.1442-200x.2009.02867.x

Cited by 15 publications

(12 citation statements)

References 10 publications

(14 reference statements)

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“…The first group presented five episodes of UTI (18.5%) against 11 (42.3%) and 18 (48.1%) episodes in groups G2 and G3 respectively (Ferrara et al, 2009). Only one work (Nishizaki et al, 2009) compared the effect of cranberry with that of an antibiotic (Cefaclor) in UTI prophylaxis. This study shows that the effect and efficacy of the two treatments are comparable and without the presence of side effects caused by cranberry juice (Nishizaki et al, 2009).…”

Section: Referencesmentioning

confidence: 99%

“…Only one work (Nishizaki et al, 2009) compared the effect of cranberry with that of an antibiotic (Cefaclor) in UTI prophylaxis. This study shows that the effect and efficacy of the two treatments are comparable and without the presence of side effects caused by cranberry juice (Nishizaki et al, 2009). The latest works in 2010 were published in abstract form in the proceedings of the Fifteenth …”

Section: Referencesmentioning

confidence: 99%

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Cranberry in children: prevention of recurrent urinary tract infections and review of the literature

Dessì¹,

Atzei²,

Fanos³

2011

Rev. bras. farmacogn.

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Urinary tract infections (UTI) are common in childhood. In 30-50% of children with UTI the infections occur recurrently, especially in those with vesicoureteral reflux (VUR), neurogenic bladder (NB), previous cystitis or pyelonephritis and malformative uropathies. To reduce the likelihood of UTI, antibiotic prophylaxis has been regarded as the therapeutic standard for many years. However, the disadvantage of long-term antibiotic therapy is the potential for development of collateral effects and resistant organisms in the host. Such reasons have induced scientists to search for alternative modalities of UTI prevention and have contributed to determining the increasing desire for "naturalness" of the population and preventing excessive medication. The use of cranberry fulfils these needs by potentially replacing or enhancing traditional procedures. The purpose of this study was to assess the effectiveness of cranberry in preventing UTI in pediatric populations. We searched Pubmed, the Cochrane Central Register of Controlled Trials and Internet. Cranberry in patients with previous UTI was evaluated in three studies, cranberry in patients with VUR in three studies and four studies analyzed the efficacy of cranberry in children with NB. In seven of nine studies cranberry had a significant effect in preventing UTI.

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Section: Referencesmentioning

confidence: 99%

Section: Referencesmentioning

confidence: 99%

Cranberry in children: prevention of recurrent urinary tract infections and review of the literature

Dessì¹,

Atzei²,

Fanos³

2011

Rev. bras. farmacogn.

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“…Nishizaki et al, 2009 Controlled clinical trial Level IV 31 children (girls = 13; boys = 18) hospitalized for vesicoureteral reflux (VUR) 100 ml of 50% concentrated cranberry juice for 3 to 27 months (intervention, n = 12) vs. 5 to 10 mg/kg cefaclor for 5 to 15 months (control, n = 19).…”

Section: Discussionmentioning

confidence: 99%

“…Despite study implementation challenges, such as compliance, failure to complete study activities, and/or other variables that may have influenced the responses, the results are mixed. Among children (Ferrara et al, 2009;Nishizaki et al, 2009), the cranberry-based intervention appeared to positively influence the prevention and/ or treatment of UTIs. Among pregnant women, the intervention prevented or reduced the number of UTIs occurring during pregnancy (Wing, Rumney, Preslicka, & Chung, 2008).…”

Section: Cranberry Juice and Cocktail Trialsmentioning

confidence: 97%

Systematic Review of the Literature: The Effectiveness of Cranberry Products to Reduce Urinary Tract Infections in Females: A Literature Review

Wang

2013

UNJ

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Cranberry products, especially cranberry juice, have been posited to prevent or treat urinary tract infections (UTIs) in females. Antimicrobial resistance has been correlated to repeated antibiotic treatment. Thus, evaluating cranberry products as a possible alternative to conventional antibiotic therapy is appropriate. This review of the literature evaluated research in which cranberry-based products are used to prevent or treat UTIs.

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“…The authors concluded that cranberry juice has comparable efficacy to cefaclor prophylaxis in pediatric patients with VUR and suggest it as an alternative to antibiotic prophylaxis. 15 The second trial, a phase III randomized study, by Uberos and colleagues 16 compared the effects of cranberry juice to trimethoprim. Patients and researchers were blinded to the treatment options.…”

Section: Studies In Children With Anatomical Abnormalitiesmentioning

confidence: 99%

Cranberry Products for the Prophylaxis of Urinary Tract Infections in Pediatric Patients

2015

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Can cranberry juice be a substitute for cefaclor prophylaxis in children with vesicoureteral reflux?

Cited by 15 publications

References 10 publications

Cranberry in children: prevention of recurrent urinary tract infections and review of the literature

Cranberry in children: prevention of recurrent urinary tract infections and review of the literature

Systematic Review of the Literature: The Effectiveness of Cranberry Products to Reduce Urinary Tract Infections in Females: A Literature Review

Cranberry Products for the Prophylaxis of Urinary Tract Infections in Pediatric Patients

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