Protective effect of early placement of nasogastric tube with solid dilator on tissue damage and stricture formation after caustic esophageal burns in rabbits

Defagó, Victor; Moyano, Jimena; Bernhardt, Celina; Sambuelli, Gabriela; Cuestas, Eduardo

doi:10.1016/j.jpedsurg.2014.11.040

Cited by 3 publications

(2 citation statements)

References 27 publications

(28 reference statements)

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“…Stenosis Index and lumen diameter were significantly lower in the treated group than the untreated group. It was concluded that an early placement of an intraesophageal tube with a solid dilator prevents stenosis formation and does not produce greater tissue damage[ 28 ]. To limit acid reflux it would be prudent to add an acid suppressant in the presence of a nasogastric tube.…”

Section: Dilemmas In Acute Corrosive Ingestion Managementmentioning

confidence: 99%

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Corrosive upper gastrointestinal strictures in children: Difficulties and dilemmas

Sarma¹,

Tripathi²,

Arora³

2021

WJCP

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Children constitute 80% of all corrosive ingestion cases. The majority of this burden is contributed by developing countries. Accidental ingestion is common in younger children (< 5 years) while suicidal ingestion is more common in adolescents. The severity of injury depends on nature of corrosive (alkali or acid), pH, amount of ingestion and site of exposure. There are multiple doubts and dilemmas which exist in management of both acute ingestion and chronic complications. Acute ingestion leads to skin, respiratory tract or upper gastrointestinal damage which may range from trivial to life threatening complications. Esophagogastroduodenoscopy is an important early investigation to decide for further course of management. The use of steroids for prevention of stricture is a debatable issue. Upper gastrointestinal stricture is a common long-term sequelae of severe corrosive injury which usually develops after three weeks of ingestion. The cornerstone of management of esophageal strictures is endoscopic bougie or balloon dilatations. In case of resistant strictures, newer adjunctive therapies like intralesional steroids, mitomycin and stents can be utilized along with endoscopic dilatation. Surgery is the final resort for strictures resistant to endoscopic dilatations and adjunctive therapies. There is no consensus on best esophageal replacement conduit. Pyloric strictures require balloon dilatation , failure of which requires surgery. Patients with post-corrosive strictures should be kept in long term follow-up due to significantly increased risk of carcinoma. Despite all the endoscopic and surgical options available, management of corrosive stricture in children is a daunting task due to high chances of recurrence, perforation and complications related to poor nutrition and surgery.

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Section: Dilemmas In Acute Corrosive Ingestion Managementmentioning

confidence: 99%

“…Adequate calories should be provided due to a high catabolic state. In rabbits models, it was found that weight gain is significantly higher after 22 d of caustic ingestion in those animals with nasogastric tubes[ 28 ]. Nasoenteric tubes must be placed under endoscopic or fluoroscopic vision.…”

Section: Dilemmas In Acute Corrosive Ingestion Managementmentioning

confidence: 99%