Abstract:Protection of skin cells from chronic infrared-A (IRA) irradiation is crucial for anti-photoaging of the skin. In this study, we investigated the protective activity of Rg3(S) and Rg3(S)-incorporated anionic soybean lecithin liposomes (Rg3/Lipo) with a size of approximately 150 nm against IRA-induced photodamage in human fibroblasts. The formulated Rg3/Lipo showed increased solubility in aqueous solution up to a concentration of 200 μg/ml, compared to free Rg3(S). In addition, Rg3/Lipo exhibited superior collo… Show more
“…73 Moreover, Rb1 and Rg3(S) can alleviate or prevent UVB-induced apoptosis. 70,74 However, not all differential isomers have antiaging activity. For example, 20 (S)-Rg3 scavenges ROS and inhibits the activity of MMP-2, whereas 20(S)-Rg3 does not have any activity.…”
With the acceleration of global aging and the rise in living standard, the achieving of healthy aging is becoming an imperative issue globally. Ginseng, a medicinal plant that has a...
“…73 Moreover, Rb1 and Rg3(S) can alleviate or prevent UVB-induced apoptosis. 70,74 However, not all differential isomers have antiaging activity. For example, 20 (S)-Rg3 scavenges ROS and inhibits the activity of MMP-2, whereas 20(S)-Rg3 does not have any activity.…”
With the acceleration of global aging and the rise in living standard, the achieving of healthy aging is becoming an imperative issue globally. Ginseng, a medicinal plant that has a...
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