Protecting children from lead poisoning and building healthy communities.

Ryan, Don; Lévy, Bernard; Pollack, Seymour L.; Walker, Ben

doi:10.2105/ajph.89.6.822

Cited by 19 publications

(14 citation statements)

References 6 publications

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“…12 Therefore, lead toxicity to human organs and systems has been extensively documented for over two millennia. 13 Lead poisoning for more than a century has been the most prevalent and serious disease of environmental origin for young children in the United States. 14 Air borne lead, particularly lead which has settled in the dust and dirt is gradually being recognized as an important hazardous source of exposure in children.…”

Section: Introductionmentioning

confidence: 99%

The Effect of lead exposure of mice during pregnancy on the morphology of epididymal and testicular spermatozoa of their offspring

Im¹,

In²,

MB³

et al. 2009

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Introduction: The aims of this study were to assess the differences in the percentages of abnormal morphology between the epididymal and testicular spermatozoa of mature male offspring mice whose mothers were injected with various doses of lead acetate during gestation. Materials and Methods: Seventy two healthy female mice were divided into three major groups according to the number of injections involving 1, 2 or 3 injections at 8th day; 8th and 13th days; and 8th, 13th and 18th days of gestation period, respectively. Each major group was subdivided into four minor groups according to the dosage of lead administered (0, 25, 50 and 100) mg/Kg. Results: The percentages of abnormal morphology of epididymal and testicular spermatozoa were studied and the data were statistically analyzed. The results of this study proved that an increased number of injections and/or dose of lead acetate injected to the mothers during gestation cause an elevation in the percentage of abnormal morphology of both epididymal and testicular spermatozoa of the male mice offspring. Conclusion: In conclusion this study demonstrated that lead acetate when exposed prenatally have toxic effects on the sperm in the offspring male mice resulting in abnormal morphology of spermatozoa. The most likely causative factor is disturbances in the phase(s) of spermatogenesis and/or spermiogenesis.

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Section: Introductionmentioning

confidence: 99%

The Effect of lead exposure of mice during pregnancy on the morphology of epididymal and testicular spermatozoa of their offspring

Im¹,

In²,

MB³

et al. 2009

imjm

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“…Recent estimates put the number at 0.9 Million (890,000) preschool children in the United States (Ryan et al, 1999).…”

Section: Emerging Data On Lead and Declining Level Of Toxic Dosementioning

confidence: 99%

Environmental chemicals and human neurotoxicity: magnitude, prognosis and markers

Anetor¹,

Anetor²,

Iyanda³

et al. 2010

African Journal of Biomedical Research

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“…21 Recognition and regulation have led to an abatement of this problem, so that blood lead concentrations in children have declined dramatically, 22 although there are still areas where children are at high risk. 23 …”

Section: Lead Poisoningmentioning

confidence: 99%