Abstract:Background: Human papillomavirus (HPV)-associated oropharyngeal cancer occasionally has a poor prognosis, making prognostic risk strati cation crucial. Protease-activated receptor-1 (PAR1) is involved in carcinogenesis and is regulated by alpha-arrestin domain-containing protein 3 (ARRDC3). It is also involved in the tumor microenvironment. We sought to evaluate the predictive ability of PAR1, ARRDC3, and tumorin ltrating lymphocyte (TIL) scores in patients with oropharyngeal, hypopharyngeal, and uterine cervi… Show more
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