“…In general, diphtheroids (non-C. diphtheriae corynebacteria) are relatively nonpathogenic and are primarily opportunistic pathogens in persons with valvular heart disease or prosthetic valves or both (12,13,21,24,25) and in compromised hosts (27). The incidence of infection of prosthetic valves is approximately 2.6% (9,34) and is associated with high mortality rates seen in PVE caused by fungi (93%), Staphylococcus aureus (86%), diphtheroids (64%), Staphylococcus epidermidis (63%), and gram-negative bacilli (60%) (34).…”