1996
DOI: 10.1056/nejm199608083350607
|View full text |Cite
|
Sign up to set email alerts
|

Prosthetic Heart Valves

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1

Citation Types

5
326
1
16

Year Published

1999
1999
2015
2015

Publication Types

Select...
10

Relationship

0
10

Authors

Journals

citations
Cited by 644 publications
(348 citation statements)
references
References 88 publications
5
326
1
16
Order By: Relevance
“…317 Thrombotic occlusion of a prosthetic valve has an incidence of 0.5% to 6% per patient-year. [335][336][337][338][339] The risk of valve thrombosis is not linear and is more frequent early after replacement. Presentation of patients ranges from asymptomatic to cardiogenic shock.…”
Section: Recommendations For Long-term Prevention Ofmentioning
confidence: 99%
“…317 Thrombotic occlusion of a prosthetic valve has an incidence of 0.5% to 6% per patient-year. [335][336][337][338][339] The risk of valve thrombosis is not linear and is more frequent early after replacement. Presentation of patients ranges from asymptomatic to cardiogenic shock.…”
Section: Recommendations For Long-term Prevention Ofmentioning
confidence: 99%
“…Anticoagulant therapy is required in patients with a mechanical prosthetic heart valve to prevent stroke and systemic embolism, and to prevent valve thrombosis, which is associated with a 15% mortality rate [13,14]. Patients with a prosthetic mitral valve, a caged-ball valve, and two prosthetic heart valves are at highest risk for thromboembolic events [15]. Patients with a prosthetic aortic valve and two or more thromboembolic risk factors may be considered at moderate risk for thromboembolic events, whereas patients with a prosthetic aortic valve and less than two thromboembolic risk factors are at lowest risk.…”
Section: Discussionmentioning
confidence: 99%
“…Glutaraldehyde has been widely used as a tissue fixative for these bioprosthetic valves and vascular grafts due to its ability to produce collagen crosslinking, reduce tissue antigenicity and sterilize the valves [27]. Bioprosthetic valves have a possibility of the prosthetic valve failure due to calcification, pannus formation and tissue degeneration; several reagents have been extensively investigated to inhibit them [5,22].…”
Section: Discussionmentioning
confidence: 99%