Prostatakarzinomdiagnostik durch Ultraschallelastographie

Sommerfeld, H.-J.; Garcia-Schürmann, J. M.; Schewe, Jens-Christian; Kühne, K.-H.; Cubick, F.; Berges, Richard; Lorenz, A.; Pesavento, A.; Scheipers, S.; Ermert, H.; Pannek, Jürgen; Philippou, Stathis; Senge, Th.

doi:10.1007/s00120-003-0297-4

Cited by 16 publications

(3 citation statements)

References 13 publications

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“…[ 6 43 ] Elastography has already proved its valuable clinical utility in applications such as breast cancer diagnosis[ 44 45 46 47 48 49 ] or assessment of liver fibrosis,[ 43 50 51 52 53 54 55 56 57 58 ] adding complementary information to conventional US. It has also shown promising results in applications such as thyroid nodules,[ 59 60 ] pancreatic masses,[ 19 21 28 61 62 ] chronic pancreatitis,[ 42 63 64 ] autoimmune pancreatitis,[ 65 ] prostate cancer,[ 66 67 68 ] or LNs assessment. [ 69 ] Recently, elastography has been also introduced during EUS examination.…”

Section: What Is Elastography?mentioning

confidence: 99%

Endoscopic ultrasound: Elastographic lymph node evaluation

et al. 2015

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Different imaging techniques can bring different information which will contribute to the final diagnosis and further management of the patients. Even from the time of Hippocrates, palpation has been used in order to detect and characterize a body mass. The so-called virtual palpation has now become a reality due to elastography, which is a recently developed technique. Elastography has already been proving its added value as a complementary imaging method, helpful to better characterize and differentiate between benign and malignant masses. The current applications of elastography in lymph nodes (LNs) assessment by endoscopic ultrasonography will be further discussed in this paper, with a review of the literature and future perspectives.

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Section: What Is Elastography?mentioning

confidence: 99%

Endoscopic ultrasound: Elastographic lymph node evaluation

et al. 2015

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“…These methods (summarized in a review by Greenleaf et al (2003)) interrogate tissue mechanical properties and produce images that are generally representative of underlying tissue stiffness. Elasticity imaging methods have shown clinical promise for in vivo detection of malignancies located in the breast (Cespedes et al 1993, Garra et al 1997, McKnight et al 2002, Bercoff et al 2003, Sharma et al 2004, Sinkus et al 2005, Itoh et al 2006, Insana et al 2004, prostate (Lorenz et al 1999, Cochlin et al 2002, Souchon et al 2003, Sommerfeld et al 2003, Konig et al 2005 and other organs (Chakraborty et al 2006, Lyshchik et al 2005. Further, direct mechanical measurements of resected liver samples have indicated that elastic contrast also exists for many tumors in the liver (Yeh et al 2002).…”

Section: Introductionmentioning

confidence: 99%

In vivo visualization of abdominal malignancies with acoustic radiation force elastography

et al. 2007

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The utility of acoustic radiation force impulse (ARFI) imaging for real-time visualization of abdominal malignancies was investigated. Nine patients presenting with suspicious masses in the liver (n = 7) or kidney (n = 2) underwent combined sonography/ARFI imaging. Images were acquired of a total of 12 tumors in the nine patients. In all cases, boundary definition in ARFI images was improved or equivalent to boundary definition in B-mode images. Displacement contrast in ARFI images was superior to echo contrast in B-mode images for each tumor. The mean contrast for suspected hepatocellular carcinomas (HCCs) in B-mode images was 2.9 dB (range: 1.5-4.2) versus 7.5 dB (range: 3.1-11.9) in ARFI images, with all HCCs appearing more compliant than regional cirrhotic liver parenchyma. The mean contrast for metastases in B-mode images was 3.1 dB (range: 1.2-5.2) versus 9.3 dB (range: 5.7-13.9) in ARFI images, with all masses appearing less compliant than regional non-cirrhotic liver parenchyma. ARFI image contrast (10.4 dB) was superior to Bmode contrast (0.9 dB) for a renal mass. To our knowledge, we present the first in vivo images of abdominal malignancies in humans acquired with the ARFI method or any other technique of imaging tissue elasticity.

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“…The sample height (L ph (cs)) is determined by finding the distance between the imaging window and the compression plate in the OCT images. The change in phantom height was used to calculate the strain in between each compression step (2).…”

Section: F Ground Truthmentioning

confidence: 99%

Quantitative Optical Coherence Elastography: A Novel Intensity-Based Inversion Method Versus Strain-Based Reconstructions

Krainz

Sherina

Hubmer

et al. 2023

IEEE J. Select. Topics Quantum Electron.

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Many diseases like cancer or atherosclerosis bear micro-scale tissue stiffness changes, which can be visualised by optical coherence elastography (OCE). OCE is a promising research field, where a growing number of publications present qualitative displacement maps. Quantitative OCE results have also been presented, but still lack high precision and good reproducibility, which are important for clinical applications. In this work, we compare three reconstruction methods for the Young's modulus in intensity-based quasi-static compressional OCE: uniaxial analysis, strain map based reconstruction facilitating a particle tracking improved optical flow (EOFM), and a novel image-based inverse reconstruction method (IIM). The quality of the proposed reconstruction methods is investigated by comparing their performance on twelve silicone elastomer phantoms with inclusions of varying size and stiffness. While the uniaxial reconstruction is strongly affected by lateral motion, EOFM is capable of deriving precise strain maps from consecutive OCT images during compression. However, for a valid Young's modulus reconstruction additional stress map information is required. IIM performs best, precisely reconstructing Young's modulus of inclusion and background, closely corresponding to separately determined ground truth values. The method offers a significant improvement of the relative error by a factor of 3.5 compared to uniaxial and strain-based analysis.

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Prostatakarzinomdiagnostik durch Ultraschallelastographie

Cited by 16 publications

References 13 publications

Endoscopic ultrasound: Elastographic lymph node evaluation

Endoscopic ultrasound: Elastographic lymph node evaluation

In vivo visualization of abdominal malignancies with acoustic radiation force elastography

Quantitative Optical Coherence Elastography: A Novel Intensity-Based Inversion Method Versus Strain-Based Reconstructions

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