Prospective study of voice outcomes and patient tolerance of in‐office percutaneous injection laryngoplasty

Bırkent, Hakan; Sardesaı, Maya G.; Hu, Amanda; Meratı, Albert L.

doi:10.1002/lary.24010

Cited by 32 publications

(54 citation statements)

References 18 publications

(37 reference statements)

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“…The UVFP cohort was found to have statistically significant ( P < 0.05, t test) poorer voice quality on CAPE‐V. The CAPE‐V = 29.6 (21.6) voice outcome of the UVFP cohort in this pilot study was consistent with a report on voice outcome in 35 consecutive study patients treated by office‐based injection laryngoplasty for glottal insufficiency, 20 with either vocal fold paralysis or paresis, for which CAPE‐V = 31.0 (21.9) …”

Section: Resultssupporting

confidence: 85%

Vocal motor control and central auditory impairments in unilateral vocal fold paralysis

et al. 2018

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Objectives To evaluate differences in vocal motor control and central auditory processing between treated unilateral vocal fold paralysis (UVFP) and healthy control cohorts. Study Design Cross‐sectional. Methods Ten UVFP study patients treated by type I thyroplasty with stable voices were compared to 12 control subjects for vocal motor control using a pitch perturbation response task and central auditory processing performance using a battery of complex sound intelligibility assays that included adverse temporal and noise conditions. Standard clinical evaluations of voice production and peripheral audiometric sensitivity were performed. Results Vocal motor control was impaired in treated UVFP. The UVFP cohort exhibited a 32.5% reduction in the instantaneous, subconscious compensatory response to pitch feedback perturbation in the interval between 150 ms and 550 ms following onset (P < 0.0001, linear mixed effects model). This impairment cannot simply be ascribed to vocal motor capacity insufficiency in the UVFP cohort because both cohorts demonstrated comparable functional capacity to perform the vocal motor task. The UVFP cohort also showed greater propensity for central auditory processing impairment (P < 0.05), notably for temporal compression and added noise challenges. Conclusion Combined central vocal motor control and auditory processing impairments in treated UVFP highlight reciprocal interdependency of sensory and motor systems. This pilot study suggests that peripheral motor impairment of the larynx can degrade central auditory processing, which in turn may contribute to vocal motor control impairment. A more complete restoration communicative function in UVFP will require deeper understanding of sensory, motor, and sensorimotor aspects of the human communication loop. Level of Evidence 3b Laryngoscope, 129:2112–2117, 2019

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Section: Resultssupporting

confidence: 85%

Vocal motor control and central auditory impairments in unilateral vocal fold paralysis

et al. 2018

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“…Injection laryngoplasty is an established treatment for glottic insufficiency secondary to vocal fold paralysis, paresis, or atrophy. 16 It is performed under general anesthetic via a transoral approach or as an in-office procedure under local anesthetic via a transoral or a percutaneous approach. Injection laryngoplasty does not alter the vocal fold length or tension, as is achieved by the methods described previously.…”

Section: Discussionmentioning

confidence: 99%

Bilateral In-Office Injection Laryngoplasty as an Adjunctive Treatment for Recalcitrant Puberphonia: A Case Report and Review of the Literature

2016

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“…The procedure is generally well tolerated [46,47], with most patients stating they would repeat the procedure without hesitation if necessary. Discomfort may be quite sharp during the injection, with referral of pain to the ipsilateral ear via Arnold's nerve.…”

Section: Perioperative Care and Complicationsmentioning

confidence: 99%

In-Office Laryngeal Injection

Sulica

Mor

2015

Curr Otorhinolaryngol Rep

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Originally described more than a century ago, vocal fold injection in the awake, unsedated patient has returned to routine clinical use because of improved injectable materials and flexible laryngoscopy optics. The vocal fold may be injected via a number of approaches to remedy conditions of glottic insufficiency including vocal fold paralysis and paresis, atrophy, and scar. Its use in the treatment of treating benign mass lesions is an evolving topic. Trial injections may be performed in cases of uncertain benefit, a use which has revealed the importance of glottic insufficiency in an unexpected variety of complaints. Injection materials are generally well tolerated, although injection into the superficial tissues of the vocal folds is to be avoided. Although laryngeal injection in the awake patient demands some technical expertise and finesse, procedure completion rates are high with low rates of complications, comparable to injection under anesthesia.

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Prospective study of voice outcomes and patient tolerance of in‐office percutaneous injection laryngoplasty

Abstract: Injection laryngoplasty is an effective method of treating glottal insufficiency, as measured by voice outcomes. Patients have realistic expectations on the procedure experience and find it tolerable. This is the first prospective study of injection laryngoplasty outcomes.

Cited by 32 publications

References 18 publications

Vocal motor control and central auditory impairments in unilateral vocal fold paralysis

Vocal motor control and central auditory impairments in unilateral vocal fold paralysis

Bilateral In-Office Injection Laryngoplasty as an Adjunctive Treatment for Recalcitrant Puberphonia: A Case Report and Review of the Literature

In-Office Laryngeal Injection

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