2016
DOI: 10.1002/jso.24344
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Prospective randomized controlled study to assess the value of a hemostatic and sealing agent for preventing seroma after axillary lymphadenectomy

Abstract: Use of a collagen sponge coated with human coagulation factors following axillary lymphadenectomy was associated to a lower incidence of postoperative seroma. J. Surg. Oncol. 2016;114:423-427. © 2016 Wiley Periodicals, Inc.

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Cited by 13 publications
(10 citation statements)
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References 45 publications
(44 reference statements)
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“…One study was excluded from the analysis due to its retrospective nature [ 13 ]. At the end of the selection process, 23/223 (10.3%) screened studies met the inclusion criteria [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]. Figure 1 shows the PRISMA flow chart outlining the process of evidence acquisition.…”
Section: Resultsmentioning
confidence: 99%
See 2 more Smart Citations
“…One study was excluded from the analysis due to its retrospective nature [ 13 ]. At the end of the selection process, 23/223 (10.3%) screened studies met the inclusion criteria [ 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 ]. Figure 1 shows the PRISMA flow chart outlining the process of evidence acquisition.…”
Section: Resultsmentioning
confidence: 99%
“…Among them, 1884 (94.8%) patients had breast cancer; the remaining 103 and 1 patients were affected by melanoma and other cancers, and Hodgkin’s disease, respectively. In one of the series, one patient with Hodgkin’s disease underwent an axillary dissection [ 27 ]. The authors do not comment on the reason why they subjected the patient to this procedure.…”
Section: Resultsmentioning
confidence: 99%
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“…The reduction of dead space after surgery is one of those strategies that can be achieved through chemical ( 25 ) and/or mechanical means ( 26 , 27 ). Fibrin enriched compounds have shown seroma reduction in smaller studies, but this effect was lost in large randomized trials ( 23 , 24 , 26 , 28 ). Surgical glue has many uses, particularly in pediatric urogenital operations, to decrease incidence of hematomas, leak, and in the treatments of lymphocele ( 24 , 29 , 30 ).…”
Section: Introductionmentioning
confidence: 99%
“…No consensus exists despite numerous suggested strategies to reduce seroma formation including drains, buttress sutures, fibrin glue or patches, tetracycline sclerosing agents, methylprednisolone, somatostatin, and shoulder exercises (13,(15)(16)(17)(18)(19)(20)(21)(22)(23)(24).…”
Section: Introductionmentioning
confidence: 99%