Prospective Evaluation of Lesion Index-Guided Pulmonary Vein Isolation Technique in Patients with Paroxysmal Atrial Fibrillation: 1-year Follow-Up.

Mattia, Luca De

doi:10.4022/jafib.1858

Cited by 41 publications

(44 citation statements)

References 22 publications

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“…For TACTICATH catheter, the contact force targeted before lesion delivery is 10 to 40 g, with a minimum individual lesion duration of 400 g-seconds-force-time integral. A target lesion size index of 5.0 to 5.5 at posterior wall and 5.5 to 6.0 at anterior and septal wall was achieved in all of our patients [19] , [20] . For SMARTTOUCH catheter, ablation index was used (550 for anterior and roof and 400 for posterior and inferior LA segments [21] , [22] , [23] .…”

Section: Methodsmentioning

confidence: 52%

Catheter ablation for atrial fibrillation in a low-volume center using contemporary technology

Tay

Cai

Lin

et al. 2020

IJC Heart & Vasculature

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Highlights There has been significant heterogeneity in the definition of what constitutes as low volume operator /center for AF ablation. Current literature suggests lower success rates but higher complications rates in low-volume centers. First AF catheter ablation in a low-volume center has comparable safety and efficacy outcomes to high-volume centers using contemporary ablation technologies.

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Section: Methodsmentioning

confidence: 52%

Catheter ablation for atrial fibrillation in a low-volume center using contemporary technology

Tay

Cai

Lin

et al. 2020

IJC Heart & Vasculature

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“…LSI incorporates CF between the tissue and the ablation tip, current, and duration of RF application as well as a resistive and conductive tissue‐heating component. For a detailed description of LSI, see Mattia et al 12,17 …”

Section: Methodsmentioning

confidence: 99%

“…LSI incorporates CF between the tissue and the ablation tip, current, and duration of RF application as well as a resistive and conductive tissue-heating component. For a detailed description of LSI, see Mattia et al 12,17 Pig hearts were obtained from a local butcher and placed in a chamber containing physiologic saline solution at room temperature. The solution was circulated using an external pump at a rate of 5 L/min.…”

Section: Methodsmentioning

confidence: 99%

The force stability of tissue contact and lesion size index during radiofrequency ablation: An ex‐vivo study

Parwani

Hohendanner

Bode

et al. 2020

Pacing Clinical Electrophis

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Introduction Radiofrequency (RF) ablation is a commonly used tool in the invasive electrophysiology laboratory to treat a variety of rhythm disorders. Reliable creation of transmural ablation lesions is crucial for long‐term success. Lesion size index (LSI) is a multiparametric index that incorporates time, power, contact force (CF), and impedance data recorded during RF ablation in a weighted formula and has been shown to predict the extent of myocardial tissue lesions. Whether the force stability of contact influences lesion size in LSI‐guided ablations is unknown. Objectives The aim of this study was to analyze the influence of the force stability of contact on lesion size during LSI‐guided ablations in an ex‐vivo model. Methods and Results A total of 267 RF lesions (n = 6 hearts) were created on porcine myocardial slabs by using an open‐tip irrigated ablation catheter with the following settings: 35 W with either intermittent (varied between 0 and up to 20 g), variable (10 to 20 g), or constant tissue contact (15 g) in a perpendicular or parallel fashion (applied manually) up to a target LSI of either 5 or 6. Subsequently, lesion width and depth were determined. Lesion width was mainly influenced by catheter tip orientation and LSI, whereas lesion depth was mainly influenced by LSI alone. The force stability of catheter contact had no relevant impact on lesion width or depth. Conclusion The force stability of catheter contact has only little effect on lesion depth or width in LSI‐guided catheter ablation while the catheter orientation primarily affects lesion width.

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“…There are many parameters that can guide RF ablation during an AF ablation such as a reduction in bipolar voltage amplitude of the near-field electrogram, noncapture of the underlying myocardium, 9 predefined drops in impedance, and use of proprietary algorithms like force-time integral, Visitag R , Ablation Index R , and Lesion size index R . 15,16 However, none of these parameters have been validated for HPSD RF energy application. Modification of unipolar waveform by means of the complete elimination of the negative component may serve as an end-point for HPSD lesions.…”

Section: What Is the End-point Of A Hpsd Lesion?mentioning

confidence: 99%

How much is enough? An appraisal of high‐power short‐duration radiofrequency ablation for pulmonary vein isolation

Raja

Sanders

Pathak

2019

Cardiovasc electrophysiol

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Prospective Evaluation of Lesion Index-Guided Pulmonary Vein Isolation Technique in Patients with Paroxysmal Atrial Fibrillation: 1-year Follow-Up.

Abstract: In this first prospective study, LSI-guided PVI improved clinical outcome without any increase in complication rate when compared with standard, non-LSI-guided approach.

Cited by 41 publications

References 22 publications

Catheter ablation for atrial fibrillation in a low-volume center using contemporary technology

Catheter ablation for atrial fibrillation in a low-volume center using contemporary technology

The force stability of tissue contact and lesion size index during radiofrequency ablation: An ex‐vivo study

How much is enough? An appraisal of high‐power short‐duration radiofrequency ablation for pulmonary vein isolation

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