Prospect of Metal Ceramic (Titanium-Wollastonite) Composite as Permanent Bone Implants: A Narrative Review

Shanmuganantha, Lohashenpahan; Baharudin, Azmi; Sulong, Abu Bakar; Shamsudin, Roslinda; Ng, Min Hwei

doi:10.3390/ma14020277

Cited by 12 publications

(11 citation statements)

References 139 publications

(63 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Additionally, although metal implants are bioinertthat is, cells merely enclose them without responding to themthey do not stimulate the formation of healthy tissue. 21 For a metal ceramic hybrid, for the majority of bone biomaterial implants, titanium-HA has been widely adopted as the standard. It not only has titanium's strength, but also the bioactivity that HA can display, resulting in a durable implant.…”

Section: Biodegradabilitymentioning

confidence: 99%

“…While α-wollastonite is infrequently found in nature, the β-wollastonite mineral is acquired as a naturally occurring silicate mineral. 21…”

Section: Introductionmentioning

confidence: 99%

“…Its application as a biomaterial is limited as not much research is done since many still prefer HA because of its closeness to the bone. 21…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, although metal implants are bioinert – that is, cells merely enclose them without responding to them – they do not stimulate the formation of healthy tissue. 21…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A review on application of biomaterials for medical and dental implants

Abraham

Sathesh

2022

Proceedings of the Institution of Mechanical Engineers, Part L:

View full text Add to dashboard Cite

Biological tissues in the body stop functioning normally at certain times due to genetic abnormalities, ageing, sickness, trauma, degeneration or accidents. Over the past few decades, biomaterials have been extensively used in the medical and dental fields. It is used as an alternate for natural bone with inflammation or mechanical integrity. The usages of biomaterials in various applications are implant materials, integral approach to promote healing of tissues, regeneration of tissues, probes and nanoparticles, biosensors and drug delivery system. Significant research and development are still being carried out for orthopaedic implants, dental screws, bone replacement, etc. Materials designed for biomedical applications have gone through three generations, with the first generation being bioinert materials, the second being bioactive and biodegradable materials and the third being molecular responses to materials (tissue level). Biocompatibility (biological and mechanical), corrosion resistance, wear resistance and osseointegration are factors to consider while using biomaterials for longer duration. Metals and their alloys, ceramics, polymers and composites are some bioimplant materials that are being used in the modern world. Some of the most important criteria for the selection or development of new biomaterials are kinds of oxide coatings generated on the surface and the mechanical properties of materials. The article reviews out categories of bioimplants and outlines the properties exhibited by various implant material, biological and mechanical factors favouring material selection, and few challenges shown by the materials.

show abstract

Section: Biodegradabilitymentioning

confidence: 99%

“…While α-wollastonite is infrequently found in nature, the β-wollastonite mineral is acquired as a naturally occurring silicate mineral. 21…”

Section: Introductionmentioning

confidence: 99%

“…Its application as a biomaterial is limited as not much research is done since many still prefer HA because of its closeness to the bone. 21…”

Section: Introductionmentioning

confidence: 99%

“…Additionally, although metal implants are bioinert – that is, cells merely enclose them without responding to them – they do not stimulate the formation of healthy tissue. 21…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A review on application of biomaterials for medical and dental implants

Abraham

Sathesh

2022

Proceedings of the Institution of Mechanical Engineers, Part L:

View full text Add to dashboard Cite

show abstract

“…Different chemical compositions and surface treatment approaches will contribute to the phase composition and crystalline properties of metallic implants and make them suitable candidates for enhanced bone regeneration upon implantation . The biggest challenges faced by metal implants are constructing them in a way such that they should imitate natural bone structures and that as they are meant for load bearing applications, they should have an equilibrium between their strength and biological properties …”

Section: Introductionmentioning

confidence: 99%

Cerium Ion-Incorporated Titanium Metal Implants of Enhanced Bioactivity for Biomedical Applications

Mathew

Venkatesan

et al. 2023

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

The enhancement in the performance of metallic bone implants based on commercially pure titanium (CP-Ti) by incorporation of cerium (Ce) ions onto the surface was evaluated. The incorporation of Ce ions onto the CP-Ti surface was carried out by a simple two-step chemical treatment method, where an initial NaOH treatment and then a subsequent treatment with different molar concentrations of ceric nitrate solution followed by heat treatment at 600 °C were carried out. The modified surfaces were observed using field emission scanning electron microscopy (FE-SEM), scanning electron microscopy−energy dispersive X-ray analysis (SEM-EDX), X-ray photoelectron spectroscopy (XPS), the laser Raman spectroscopic technique, high-resolution transmission electron microscopy (HR-TEM), and atomic force microscopy (AFM). The formation of a nanonetwork structure by the initial NaOH treatment and the replacement of Na ions with Ce ions along with different phases of TiO 2 was evident from the surface characterization results. The transition of rutile TiO 2 to anatase TiO 2 in the modified surface is evident from the Raman spectra with respect to the treatment of higher to lower concentrations of ceric nitrate solution. The presence of two different oxidation states of Ce (Ce 3+ and Ce 4+ ) and improvement in the surface wettability were also distinct in the modified samples. Thus, the incorporated Ce ions over the nanostructured titania network showed low cytotoxicity, good cell adhesion, and enhanced extracellular mineralization on MG-63 cells with better protein adsorption in BSA medium. Taken together, the thus-improved nanostructured surface morphology with the anatase TiO 2 phase and distinct extracellular mineralization in the Ce-incorporated Ti metal with good biocompatibility make it a promising candidate for bone implant applications.

show abstract