Proposal of the new name “eruptive papular collageno‐elastopathy” to unify the two indistinguishable entities, eruptive collagenoma and papular elastorrhexis

Abstract

Treatment of SJS includes symptomatic care and, in severe cases, systemic corticosteroids. Corticosteroids have adverse effects, such as immunosuppression and retardation of re-epithelialization, and consequently there are concerns over their use. 5 High-dose corticosteroids should be used with caution in patients suspected of infection-induced SJS, such as our patient. Many studies of IVIG for SJS and TEN have reported an arrest of disease progression and a reduction in the time to skin healing particularly with doses totaling more than 2 g/kg. Although the mechanisms by which IVIG counteracts SJS and TEN are not fully understood, immunomodulating effects are suspected. Therefore, high-dose IVIG would be considered as one of therapeutic options for SJS and TEN, and especially for infection-induced SJS.

Eruptive collagenomas associated with adalimumab treatment of juvenile rheumatoid arthritis

“…Nevus anelasticus is described as “perifollicular papules” and papular elastorrhexis consists of multiple, acquired, 2‐5 mm, flat, firm, painless, oval‐shaped papules; like eruptive collagenoma, these two conditions are acquired most often in childhood and adolescence and affect the upper part of the body (torso and upper extremities). Ryder and Antaya and Lee and Sung compare these three conditions, and conclude that “nevus anelasticus, papular elastorrhexis, and eruptive collagenoma are the same entity.” Other authors have also proposed that eruptive collagenoma and papular elastorrhexis are one and the same condition. Lesions resembling eruptive collagenoma both clinically and histopathologically, but arising on the neck in older individuals, have been labeled as “white fibrous papulosis of the neck.” The relationship between this condition and EC is unclear.…”

“…It should be noted that some cases labeled as “papular elastorrhexis” and “nevus anelasticus” show considerable clinical and histologic overlap with eruptive collagenomas, and may represent the same pathologic entity as eruptive collagenomas . Nevus anelasticus is described as “perifollicular papules” and papular elastorrhexis consists of multiple, acquired, 2‐5 mm, flat, firm, painless, oval‐shaped papules; like eruptive collagenoma, these two conditions are acquired most often in childhood and adolescence and affect the upper part of the body (torso and upper extremities).…”

Papular elastorrhexis: a rare and benign disease

“…Eruptive collagenoma is an acquired disease that manifests in youth and is characterized by the presence of connective tissue nevi. 7 The histopathology reveals an abnormal accumulation of components of the extracellular matrix (collagen, elastic fibers and glycosaminoglycans). 7 …”

“… 7 The histopathology reveals an abnormal accumulation of components of the extracellular matrix (collagen, elastic fibers and glycosaminoglycans). 7 …”

Multiple yellowish white papules on the trunk and upper arms

“…Papular elastorrhexis is a rare disorder characterized by multiple yellowish white small papules on the trunk and upper extremities unaccompanied by extracutaneous manifestations . It develops predominantly during adolescence without preceding skin lesion.…”