Propolis as an alternative in prevention and control of dental cavity

Machado, Bárbara Soares; Pulcino, Tarcyane Neves; Silva, Ayalla Lima; Melo, Diego Tadeu; Silva, Renata Gomes; Mendonça, Izabel Gomes

doi:10.5455/ja.20160726115117

Cited by 23 publications

(25 citation statements)

References 26 publications

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“…Nonrestorative treatments for caries aim to disrupt the decay process, particularly on smooth dental surfaces [33], and involve chemical and mechanical disorganization of biofilms by compounds such as fluoride and antimicrobial agents [34,35]. These treatments maintain the wholeness of the tooth and demonstrate adequate efficiency [36].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Antibacterial Effect of Propolis and Its Application in Mouthwash Production

Nazeri

Ghaiour

Abbasi

2019

fid

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Objectives: The purpose was to determine the antibacterial properties of propolis and to evaluate its use as an antibacterial mouthwash with minimal complications. Materials and Methods: In this experimental laboratory study, an alcoholic propolis extract was prepared. The minimum inhibitory concentration (MIC) was calculated for four bacterial species including Staphylococcus aureus (S. aureus), Streptococcus mutans (S. mutans), Lactobacillus acidophilus (L. acidophilus), and Enterococcus faecalis (E. faecalis) using agar dilution. According to the MIC, a propolis antibacterial mouthwash was produced and compared to water, chlorhexidine (CHX), and Listerine using laboratory rats for clinical examination. Salivary specimens of rats were collected at 12 hours, 1 week, and 2 weeks after using the mouthwash and examined by the real-time polymerase chain reaction (RT-PCR). Data were analyzed using one-way analysis of variance (ANOVA) and repeated measures ANOVA (α=0.05). Results: The results of agar dilution by the number of colony-forming units (CFU) showed the lowest MIC for S. aureus and the highest for L. acidophilus. The results of the RT-PCR indicated that water alone had no effect on the level of oral bacteria. Propolis mouthwash showed a significant difference with CHX and Listerine (P<0.05) in terms of the number of S. mutans, E. faecalis, and L. acidophilus colonies, while CHX and Listerine were less efficient. There was no significant difference between CHX and propolis (P=0.110) regarding S. aureus colonies, but Listerine had a lower efficacy than either (P<0.05). Conclusions: According to the results, propolis mouthwash was more efficient against the studied oral bacteria compared to CHX and Listerine.

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Section: Discussionmentioning

confidence: 99%

Evaluation of Antibacterial Effect of Propolis and Its Application in Mouthwash Production

Nazeri

Ghaiour

Abbasi

2019

fid

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“…Propolis was used by man as a traditional medicine since 300 BC (Ghisalberti, 1979, Seidel et al, 2008, Sung et al, 2017, Trusheva et al, 2007, Uzel et al, 2005, Veiga et al, 2017). Researchers stated that the healing activities of propolis were identified by Roman (Machado et al, 2017) and Greek doctors (Elnakady et al, 2017, Ferreira et al, 2017) as well as other scientists, such as Dioscorides, Galen, Aristoteles and Pliny (Castaldo and Capasso, 2002, Crane, 1997, Dobrowolski et al, 1991, Toreti et al, 2013). Similarly, physicians used propolis efficiently for the treatment of injuries during Anglo-Boer battle (De Castro, 2001, Sforcin, 2007) as well as in World War II (Lotfy, 2006, Ramos and Miranda, 2007).…”

Section: History Of Propolismentioning

confidence: 99%

“…Similarly, the antibacterial activity takes place due to its active compounds such as, aromatic compounds (caffeic acid) and flavonoids (Parolia et al, 2010) . Moreover, propolis acts as a bactericidal agent, to stop division of bacterial cell, destroy cell wall, bacterial cytoplasm (Parolia et al, 2010) and stop protein synthesis (Lotfy, 2006, Machado et al, 2017). The component of propolis such as Pinocembrin shows antibacterial activity towards Streptococcus spp.…”

Section: Biomedical Application Of Propolismentioning

confidence: 99%

Composition and functional properties of propolis (bee glue): A review

Anjum

Ullah

Khan

et al. 2019

Saudi Journal of Biological Sciences

444

387

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Propolis is a natural substance collected by honey bees from various plants such as, poplar, palm, pine, conifer secretions, gums, resins, mucilage and leaf buds. It is collected and brought very painstakingly by honey bees to be used for sealing cracks and crevices occurring in their hives. Originally, it as an antiseptic meant for preventing bee-hive from microbial infections along with preventing decomposition of intruders. Additionally, propolis has been used in folk medicine for centuries. The biological characteristics of propolis depend upon its chemical composition, plant sources, geographical zone and seasons. More than 300 compounds have been identified in propolis such as, phenolic compounds, aromatic acids, essential oils, waxes and amino acids. Many scientific articles are published every year in different international journals, and several groups of researchers have focused their attention on the chemical compounds and biological activity of propolis.

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“…Previous studies also reporting that propolis have ameliorative role against the hepatic and renal damage caused by the oxidative stress damage (Wagh, 2013). Recent researchers reported that propolis has a cytoprotective role due to its antioxidant property, which attributed to its ingredients from phenol compounds (El-Guendouz et al, 2017;Machado et al, 2016). Also, many studies have demonstrated potential positive effects of propolis on glucose metabolism in human (Afsharpour, Hashemipour, Khadem-Haghighian, & Koushan, 2017), and experimental models of diabetic rats ( El Araby, Ahmed, & Zahkouk, 2017).…”

Section: Introductionmentioning

confidence: 96%

The protective effect of propolis against aluminum chloride-induced hepatorenal toxicity in albino rats

Okail

Ibrahim

Badr

2020

JoBAZ

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Background: The use of natural products is an essential way to new pharmaceutical leads for the discovery and development of new drugs to treat diseases. Propolis (Pro) is a natural resinous product produced by honey bees. It has a strong cytoprotective effect against various exogenous toxic agents. The current study was designed to evaluate the possible protective effect of propolis against the toxicity of aluminum chloride (AlCl 3) on hepatorenal structure and function in male white albino rats. Methods: Thirty mature males of albino rat, Rattus rattus, weighing about 80-90g were divided into five groups contained 6 rats each. The first group acts as a control (received only saline solution); the second group (Al) had given orally 40 mg/kg b.w. of AlC1 3 , the third group (Pro) had administrated orally 150 mg/kg b.w. of propolis and the fourth group (Al+Pro) had given 40 mg/kg b.w. of AlCl 3 in the morning and 150 mg/kg b.w. of propolis in the evening. These four groups had given the treatments for two months. The fifth group (Al-Pro) had given 40 mg/kg b.w. of AlC1 3 chloride for one month then had given 40 mg/kg b.w. of AlCl 3 combined with 150 mg/kg b.w. of propolis for another month. Results: The AlCl 3-treated group showed a significant increase in the activities of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), acid phosphatase (AP), and lactate dehydrogenase (LDH) in the plasma. Also, glucose, total protein, albumin, creatinine, uric acid, urea, cholesterol, and triglycerides in the plasma were significantly increased. The histological examination for the liver and kidney sections revealed marked histopathological alternations. The treatment with propolis combined with AlCl 3 improved the previous mentioned biochemical and histological alterations induced by AlCl3. Conclusion: It can be concluded that the combination of propolis with AlCl 3 alleviated the toxic effects of AlCl 3. The propolis has protective influences on the hepatorenal structure and function and could be able to resist AlCl 3 intoxication.

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Propolis as an alternative in prevention and control of dental cavity

Cited by 23 publications

References 26 publications

Evaluation of Antibacterial Effect of Propolis and Its Application in Mouthwash Production

Evaluation of Antibacterial Effect of Propolis and Its Application in Mouthwash Production

Composition and functional properties of propolis (bee glue): A review

The protective effect of propolis against aluminum chloride-induced hepatorenal toxicity in albino rats

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