Propofol-induced violent coughing in a patient with Becker′s muscular dystrophy

Abstract

Propofol anesthesia is often associated with decreased incidence of gagging, coughing or laryngospasm, and provides intense suppression on airway reflex during tracheal intubation and laryngeal mask airway insertion. Propofol pretreatment is also effective in reducing the occurrence of opioid-induced coughing. These benefits are often attributed to bronchodilator and sedative effects of propofol. However, severe coughing following sedative doses of 1% propofol has not been reported so far. We report a rare case of violent coughing following low-dose propofol infusion in a patient with Becker's muscular dystrophy.

Severe Hemoperitoneum After Oocyte Retrieval Due to Ovarian Hemorrhage Possibly Caused by Violent Cough Under General Anesthesia With Propofol and Pentazocine: A Case Report and Literature Review

“…There are few reports of cough reflex due to propofol, and it is considered a rare side effect. Case reports involving severe cough attacks during propofol anesthesia have been reported [ 7 , 8 ]. However, pentazocine is an analgesic to suppress coughing during the use of narcotics such as fentanyl [ 25 ].…”

“…Complications during anesthesia, particularly during induction, include coughing and hiccups, which can induce body movements during oocyte retrieval and increase the risk of intra-abdominal organ damage due to semi-blind vaginal puncture into the abdominal cavity. Although complications such as coughing and hiccups under general intravenous anesthesia have been reported [7][8][9], there are no reports of such complications associated with anesthesia during oocyte retrieval.…”

Anesthesia management in a pediatric patient with Becker muscular dystrophy undergoing laparoscopic surgery: A case report

“…Nevertheless, when TIVA was used as the only anesthetic technique, the occurrence of postoperative respiratory depression may increase in BMD patients due to high sensitivity to opioids and muscle relaxants. Moreover, propofol may lead to profound hypotension, reduced organ perfusion, and violent coughing[ 14 ]. Due to high sensitivity and prolonged duration of action of muscle relaxants in muscular dystrophy patients, it is even suggested that muscle relaxants should be avoided[ 2 ].…”