Prophylaxis Against Febrile Convulsions With Phenobarbital

Pilgaard, S.; Hansen, Flemming Juul; Pægaard, P.

doi:10.1111/j.1651-2227.1981.tb07175.x

Cited by 8 publications

(3 citation statements)

References 7 publications

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“…A profilaxia com fenobarbital apresenta efeitos colaterais inconvenientes, que ocorrem em até 60% dos usuári-os 30,31 : hiperatividade, irritabilidade e distúrbio do sono. Além disso, embora geralmente seja considerada eficaz, há trabalhos que sugerem que o fenobarbital não é um bom agente para a profilaxia da CF.…”

Section: Tratamentounclassified

Tratamento das crises febris

Guerreiro¹

2002

J. Pediatr. (Rio J.)

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Objective: to review basic concepts of febrile seizures and the indications of specific tests. To analyze the prognosis and the medical treatment.Sources: the author reviewed the literature and presented her published data.Summary of the findings: the key points are based on the rules of the American Academy of Pediatrics designed according to a consensus about when and how to investigate febrile seizures, and indications of treatment.Conclusions: febrile seizure is a benign entity and most children will present only one seizure during their lives. There is no indication of complementary tests (electroencephalogram, lumbar puncture and neuroimaging tests) and specific treatment for this group of children. Special indications are revised.

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Section: Tratamentounclassified

Tratamento das crises febris

Guerreiro¹

2002

J. Pediatr. (Rio J.)

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“…A profilaxia com fenobarbital apresenta efeitos colaterais inconvenientes, que ocorrem em até 60% dos usuários 30,31 : hiperatividade, irritabilidade e distúrbio do sono. Além disso, embora geralmente seja considerada eficaz, há trabalhos que sugerem que o fenobarbital não é um bom agente para a profilaxia da CF.…”

Section: Tratamentounclassified

Treatment of febrile seizures

Guerreiro¹

2002

J Pediatr (Rio J)

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Objective: to review basic concepts of febrile seizures and the indications of specific tests. To analyze the prognosis and the medical treatment. Sources: the author reviewed the literature and presented her published data. Summary of the findings: the key points are based on the rules of the American Academy of Pediatrics designed according to a consensus about when and how to investigate febrile seizures, and indications of treatment. Conclusions: febrile seizure is a benign entity and most children will present only one seizure during their lives. There is no indication of complementary tests (electroencephalogram, lumbar puncture and neuroimaging tests) and specific treatment for this group of children. Special indications are revised.

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“…Among untreated children less than 14 months of age, Nelson & Ellenberg (2) found that 50% had one recurrence and 30% had more than one recurrence within the first year after the initial seizure. Among untreated children over 14 months of age the risk of recurrence has been found to be 12-30°/0 (2,3,4). After the age of 3 the risk of recurrence appears to be only 10-12% (5).…”

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Prophylactic Treatment with Valproic Acid or Diazepam in Children with Febrile Convulsions

et al. 1986

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The purpose of this study was to limit prophylactic treatment of children with febrile convulsions to patients who have the highest risk of recurrence. Two hundred and thirty-one children with a first febrile seizure were divided into high- and low-risk groups according to estimated risk of recurrence. All high-risk children were offered treatment with valproic acid. If this was declined they were offered treatment with diazepam instead. Low-risk children were untreated. Valproic acid and diazepam were found to be equally effective in reducing the risk of recurrence of febrile convulsions. By selecting for prophylactic treatment according to estimated risk of recurrence it is possible to reduce the rate of recurrence of febrile seizures in children at high-risk (60%) to the same level as that of untreated low-risk children (23%). Only about half of all children with febrile convulsions need treatment and follow-up according to these criteria.

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Prophylaxis Against Febrile Convulsions With Phenobarbital

Cited by 8 publications

References 7 publications

Tratamento das crises febris

Tratamento das crises febris

Treatment of febrile seizures

Prophylactic Treatment with Valproic Acid or Diazepam in Children with Febrile Convulsions

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