Prophylactic zinc supplementation for prevention of acute respiratory infections in infants and young children

Low serum zinc level: The relationship with severe pneumonia and survival in critically ill children

“…Various studies from India demonstrated that prevalence of zinc deficiency in apparently healthy children and adolescents ranged from 44% to 72% . Acute respiratory infection (ARI) is a leading cause of morbidity and mortality among young children in low‐ and middle‐income countries especially pneumonia with approximately 81% of pneumonia deaths occur during the first 2 years of life . Also, pneumonia is responsible for 18% of under‐five mortality as a result of an estimated 151 million new episodes each year occurring mostly in the marginalised and malnourished children in the developing countries who are often zinc‐deficient .…”

“…4 Acute respiratory infection (ARI) is a leading cause of morbidity and mortality among young children in low-and middle-income countries especially pneumonia with approximately 81% of pneumonia deaths occur during the first 2 years of life. 5 Also, pneumonia is responsible for 18% of under-five mortality as a result of an estimated 151 million new episodes each year occurring mostly in the marginalised and malnourished children in the developing countries who are often zinc-deficient. 6 Prophylactic zinc supplementation for 2 weeks may reduce the morbidity attributable to acute lower respiratory infections but the not overall rate of acute respiratory infections in infants aged 6-11 months in similar populations.…”

Pengaruh Suplementasi Seng terhadap Kejadian Tonsilitis pada Balita

“…28 Penelitian yang dilakukan oleh Malik pada bayi 6-12 bulan menunjukkan tidak ada perbedaan yang signifikan pada penurunan frekuensi kejadian ISPA antara kelompok placebo dan kelompok yang diberi intervensi seng 20mg selama 14 hari, namun terdapat penurunan lama waktu kesakitan selama periode follow up. 29 Berdasarkan tabel 3 menunjukkan rerata frekuensi kejadian tonsilitis pada kelompok kontrol 0,26 ± 0,562 dan kelompok intervensi 0,21 ± 0,419 yang berarti terdapat kecenderungan lebih rendah pada kelompok intervensi, namun belum signifikan secara statistik. Hasil skor tanda dan gejala tonsillitis juga menunjukkan kecenderungan lebih tinggi pada kelompok kontrol yaitu sebesar 1,26 ± 2,579 dibandingkan dengan kelompok intervensi sebesar 1,00 ± 1,795, meskipun secara statistik tidak terdapat perbedaan yang signifikan.…”