Prophylactic use of ivermectin against cattle myiasis caused by Cochliomyia hominivorax (Coquerel, 1858)

Patient with Tracheostomy Parasitized in Hospital by Larvae of the Screwworm,Cochliomyia hominivorax

“…According to Graham (1985), early results suggested that ivermectin may be ineffective against C. hominivorax , but more recent studies demonstrated that it can produce a significant reduction in the incidence of navel and scrotal myiasis due to C. hominivorax (Benitez et al 1997; Lombardero et al 1999). There has been an increasing number of publications reporting that a subcutaneous injection of doramectin (200 µg/kg) was up to 100% effective as a C. hominivorax prophylactic, preventing infestation of artificial wounds, umbilical or castration wounds of calves, and infestation of post-parturient cows for up to 12–14 days post-treatment (Moya-Borja et al 1997; Anziani et al 2000).…”

Efficacy of macrocyclic lactones for the control of larvae of the Old World Screw‐worm Fly (Chrysomya bezziana)

“…20 Injectable preparations of ivermectin and doramectin are known to be highly efficacious in preventing cutaneous myiases caused by larvae of the NWS, Co hominivorax. Both drugs have been reported to provide protection for periods of 12 or more days [21][22][23] but when compared under similar conditions, doramectin has been found to be the more persistent and efficacious. 13,24,25 Ivermectin has also been shown to be effective against C bezziana but, until now, there have been no published data dealing with the larvicidal activity of doramectin, eprinomectin or moxidectin.…”

An Overview of the Components of AW-IPM Campaigns against the New World Screwworm

“…A single subcutaneous injection of ivermectin (200 µg/kg), a macrocyclic lactone produced by Streptomyces avermitilis , has been effective against NWS in preventing navel strike of newborn calves and scrotal strike of castrated calves [ 81 ]. Studies involving ivermectin and abamectin activity have been reported in Argentina and Brazil under field conditions when the treatments were administered to newborn calves or at castration [ 82 , 83 ].…”