Objective: The effectiveness of a psychoeducational group intervention for HIV/AIDS-infected and affected women was examined at a large southeastern county jail facility. Method: A quasiexperimental pretest-posttest design was used to examine depression, anxiety, and trauma symptoms of women inmates. Results: A multivariate analysis of covariance yielded significant differences between the experimental and comparison groups. Subsequent analysis of covariance for each dependent variable indicated significant differences between groups as well. Effect sizes ranged from moderate to strong. Conclusions: The psychoeducational group intervention appeared to be effective in alleviating depression, anxiety, and trauma symptoms among women inmates infected and affected by HIV/AIDS.The number of women entering the jail and prison systems in the United States escalated by 202% over the past decade. Currently, women inmates account for about 9% of the entire prison population (Stephan & Jankowski, 1991), and women of color make up 57% of this group. One of the increasing health and emotional concerns of women prisoners and prisons themselves is the impact of HIV/AIDS on the jail population. To date, incarcerated women infected or affected by HIV/AIDS have received little interventive attention from corrections personnel. Despite indications that psychoeducational groups for people living with HIV/AIDS have been found to be effective in