Prolonged electrical systole in acute myocardial infarction

Puddu, Paolo Emilio; Jouve, R; Torresani, J; Sambuc, Roland; Jouve, A

doi:10.1016/s0022-0736(80)80084-7

Cited by 21 publications

(3 citation statements)

References 22 publications

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“…QT interval is physiologically longer in women than men [44], is a well-known cause of arrhythmia and death after selected drugs [45] and in the context of acute [46-50] or chronic [51-53] coronary artery disease. In non-ischemic heart diseases, women present with a high prevalence of mitral valve prolapse accompanied by increased circulating levels of catecholamines [54] which is related to longer QT interval [55]: these elements may contribute to increased risk for arrhythmias.…”

Section: Qt Interval Prolongationmentioning

confidence: 99%

Age- and Gender-Normalized Coronary Incidence and Mortality Risks in Primary and Secondary Prevention

2012

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Epidemiologic differences in ischemic heart disease incidence between women and men remain largely unexplained. The reasons of women’s “protection” against coronary artery disease (CAD) are not still clear. However, there are subsets more likely to die of a first myocardial infarction. The purpose of this review is to underline different treatment strategies between genders and describe the role of classical and novel factors defined to evaluate CAD risk and mortality, aimed at assessing applicability and relevance for primary and secondary prevention. Women and men present different age-related risk patterns: it should be important to understand whether standard factors may index CAD risk, including mortality, in different ways and/or whether specific factors might be targeted gender-wise. Take home messages include: HDL-cholesterol levels, higher in pre-menopausal women than in men, are more strictly related to CAD. The same is true for high triglycerides and Lp(a). HDL-cholesterol levels are inversely related to incidence and mortality. In primary prevention the role of statins is not completely ascertained in women although in secondary prevention these agents are equally effective in both genders. Weight and glycemic control are effective to reduce cardiovascular disease (CVD) mortality in women from middle to older age. Blood pressure is strongly and directly related to CVD mortality, from middle to older age, particularly in diabetic and over weighted women. Kidney dysfunction, defined using UAE and eGFR predicts primary CVD incidence and risk in both genders. In secondary prediction, kidney dysfunction predicts sudden death in women in conjunction with left ventricular ejection fraction evaluation. Serum uric acid does not differentiate gender-related CVD incidences, although it increases with age. Age-related differences between genders have been related to loss of ovarian function traditionally and to lower iron stores more recently. QT interval, physiologically longer in women than men, may be an index of arrhythmic risk in patients with mitral valve prolapse and increased circulating levels of catecholamines. However, there are no large population-based studies to assess this. In conjunction with novel parameters, such as inflammatory markers and reproductive hormones, classical risk score in women may be implemented in the future.

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Section: Qt Interval Prolongationmentioning

confidence: 99%

Age- and Gender-Normalized Coronary Incidence and Mortality Risks in Primary and Secondary Prevention

2012

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“…We published a few papers devoted to acute myocardial infarction and ventricular fibrillation risk [10][11][12] in which his vectorcardiagraphic ideas were lucidly applied when proposing, for the first time, QT interval measurements in orthogonal planes (3 nonconsecutive 5 Translation "We experimentally verified this system and its limitations in clinical practice. Therefore, after several tests we may conclude that scalar electrocariography and vectorcardiography are distinct but in a way similar measurement techniques of the same phenomenon so that both at the surface and inside the thorax it is possible to commute from vectorcardiogram to electrocardiograms obtained on the same plane and vice-versa, although amplitudes may present little differences."…”

mentioning

confidence: 99%

Professor André Jouve (1909-2001): A French cardiologist who was a pioneer of clinical vector-electrocardiography and cardiovascular epidemiology

Puddu

2016

Journal of Electrocardiology

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“…Overall, these results are in accordance with studies of patients with ischemic heart disease, although differences in study design are quite apparent. [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22] In this study Algra et a12 studied a very large…”

mentioning

confidence: 99%

Is QT interval prolongation a strong or weak predictor for cardiac death?

Ahnve¹

1991

Circulation

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Prolonged electrical systole in acute myocardial infarction

Cited by 21 publications

References 22 publications

Age- and Gender-Normalized Coronary Incidence and Mortality Risks in Primary and Secondary Prevention

Age- and Gender-Normalized Coronary Incidence and Mortality Risks in Primary and Secondary Prevention

Professor André Jouve (1909-2001): A French cardiologist who was a pioneer of clinical vector-electrocardiography and cardiovascular epidemiology

Is QT interval prolongation a strong or weak predictor for cardiac death?

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