Prologue: Oro-Dental-Derived Stromal Cells for Cranio-Maxillo-Facial Tissue Engineering - <i>Past, Present and Future</i>

Pérez, Sebastián E.; Haidar, Ziyad S.

doi:10.5772/intechopen.95090

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2022

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“…The first type, stromal cells, can become other types of functional mesodermal tissue cells like osteoblasts, chondroblasts, adipocytes, and myoblasts; this ability is what gives stromal cells their name depends on a set of markers that allow for recognizing them, looking for the surface antigens SH2, SH3, CD29, CD44, CD71, and CD90. However, these cells do not express the conventional HSC surface antigens CD34 and CD45 (20).…”

Section: Introductionmentioning

confidence: 97%

Molecular Process of Stem Cells in Modern Biology

Shahid¹,

Rehman²,

Hyder³

et al. 2022

PJMHS

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Stem cells have a wide range of traits, including the ability to self-renewal and differential interactions between various cell types that vary with their location within tissue and their immediate surroundings. Inhibitors of both are influenced by the cell cycle, genes involved in chromosomal rearrangements, critical developmental proteins, and signaling pathways. Wnt, Notch, Hedgehog Pathways, BMI-1, OCT3/4, ARF, NANOG, p16Ink4a, and this includes HOXB4, SOX2, and their homologous paralog, govern self-renewal. Stem cells and their molecular pathways that regulate self-renewal and differentiation hold great promise for theoretical and practical studies. Keyword: gene regulation of stem cell self-renewal and differentiation genes for BMI-1, NANOG, OCT3, OCT4, p16Ink4a, SOX2, microenvironment, ARF protein proteins 1 (hedgehog), proteins 2 (Wnt.), and receptors 3 (notch).

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Section: Introductionmentioning

confidence: 97%