Proline-Catalysed Amination Reactions in Cyclic Carbonate Solvents

Abstract

Propylene carbonate is shown to be an environmentally friendly and sustainable replacement for dichloromethane and acetonitrile in proline-catalysed α-hydrazinations of aldehydes and ketones. Enantioselectivities comparable to those obtained in conventional solvents or ionic liquids can be obtained, even when using a lower catalyst loading.

Non-Covalent Supported of l-Proline on Graphene Oxide/Fe3O4 Nanocomposite: A Novel, Highly Efficient and Superparamagnetically Separable Catalyst for the Synthesis of Bis-Pyrazole Derivatives

“…In recent years, amino acids, especially l -proline and proline-derivatives, have attracted much attention as promising catalysts for essential transformations in the fine chemical and pharmaceutical industries [ 22 , 23 , 24 ]. l -proline amino acid has been used more and more as catalyst, and is commercially available at low cost, but often employed at high catalyst loading as high as 30 mol % [ 25 ].…”

Coupling Reactions of Carbon Dioxide with Epoxides Catalyzed by Vanadium Aminophenolate Complexes

“…It is worth noting that carbonate structural motifs are also found in natural products . Another application of cyclic carbonates, which has grown significantly in recent years, is as green polar aprotic solvents because of their excellent solubilizing properties and relatively low toxicities. This has also led to their use as electrolyte solvents in lithium‐ion batteries …”

WITHDRAWN: Silica-supported N-alkyl DABCO incorporating different anions: efficient heterogeneous catalysts for the transformation of epoxides to cyclic carbonates

“…6 Cyclic carbonate products are widely used as polar aprotic solvents in synthesis, raw materials for polycarbonates, and intermediates in the production of fine chemicals. [7][8][9][10][11][12][13] To synthesize cyclic carbonates, numerous catalysts such as phosphines, 14 quaternary ammonium and phosphonium salts, 15 organometallic complexes, [16][17][18] alkali metal salts [19][20][21] and various ionic liquids 22,23 have been proposed. He and co-workers recently described the use of DABCO based ammonium salts as catalysts toward the chemical fixation of CO 2 with epoxides and aziridines.…”