Prolene–Monocryl-composite meshes do not increase microvascular Staphylococcus aureus adherence and do not sensitize for leukocytic inflammation

Abstract

Implanted Ultrapro meshes do neither increase microvascular Staphylococcus aureus adherence nor sensitize for leukocytic inflammation. Thus, we suggest that a mesh-induced increase of bacterial adherence in vessels of the implantation site cannot be considered as a primary cause for the development of mesh infection.

In vitro and in vivo evaluation of a novel nanosize hydroxyapatite particles/poly(ester-urethane) composite scaffold for bone tissue engineering

“…In four different microvascular regions of interest (ROIs) in the border zone of the scaffolds we measured leukocyte-endothelial cell interaction within host postcapillary or collecting venules (diameter: $40 lm). For this purpose, the leukocytes were classified according to their interaction with the vascular endothelium as adherent, rolling or free-flowing cells [18]. Adherent leukocytes were defined in each vessel segment as cells that did not move or detach from the endothelial lining within an observation period of 20 s, and are given as number of cells per mm 2 of endothelial surface, calculated from the diameter and length of the vessel segment studied, assuming a cylindrical vessel geometry.…”

Perioperative steroid administration inhibits angiogenic host tissue response to porous polyethylene (medpor®) implants

“…Leukocytes were classified according to their interaction with the vascular endothelium as rolling or adherent cells (Roller et al, 2008). Rolling leukocytes were defined as cells moving with a velocity less than two-fifths of the centreline velocity, and are expressed as number of cells per minute, passing a reference point within the microvessel.…”

Heme oxygenase (HO)-1 protects from lipopolysaccharide (LPS)-mediated liver injury by inhibition of hepatic leukocyte accumulation and improvement of microvascular perfusion

“…For the measurements, five postsinusoidal venules (diameter: ∼20-40 µm) fed by draining sinusoids were selected randomly. Within these vessels leukocytes were classified according to their interaction with the microvascular endothelium as rolling or adherent [15,16]. Rolling leukocytes were defined as cells moving with a velocity less than two fifths of the centerline velocity and are given as number of cells per minute, passing a reference point within the microvessel.…”