Prolactin and growth hormone secretion after thyrotrophin-releasing hormone infusion and dopaminergic (DA2) blockade in infertile patients with minimal/mild endometriosis

Abstract

Decreased serum estradiol levels and altered PRL secretion after TRH administration in infertile patients with minimal/mild endometriosis are related to ovulatory dysfunction and infertility in this group of patients without tubal occlusion.

Prolactin and cortisol levels in women with endometriosis

“…the present results and in agreement with most of the evidence reported in the literature (14)(15)(16)(17).…”

The effects of ergot and non-ergot-derived dopamine agonists in an experimental mouse model of endometriosis

“…In this regard, and given that prolactin (PRL) secretion has been shown to promote angiogenesis by signaling through specific blood vessel receptors (Reese et al 2000), it is possible that the reduction of circulating PRL levels as a result of DRD2 also contributes to the inhibition of the angiogenic response induced by these drugs in endometrial implants. Although there are several reports of an association between endometriosis and hyperprolactinemia (Gregoriou et al 1999, Cunha-Filho et al 2002, the existence of a fundamental proangiogenic role for PRL in human endometrial ectopic tissue is yet to be confirmed.…”

The significance of prolactin in the pathogenesis of genital endometriosis and the possibilities of dopamine agonist therapy

“…Следует отметить, что эстрогены, напротив, ак-тивно секретируются самими гетеротопиями и определя-ются в перитонеальной жидкости в высокой концентра-ции. То что повышенная секреция пролактина носит цен-тральный характер, указывают и тесты с метоклопрами-дом и тиролиберином у больных НГЭ [21]. Хотя эктопиче-ская продукция пролактина -довольно редкое явление, она описана при карциноме бронхов, гипернефроме [5].…”