“…These cases are strikingly similar to NMO, whose pathology also involves both gray-and white-matter necrosis as well as vascular hyalinization (Lucchinetti et al, 2002). The potential relationship between paraneoplastic myelopathy and NMO has previously been suggested (Katz and Ropper, 2000;Okai et al, 2006). Vascular hyalinization, frequently observed in cases of necrotizing myelopathy, is a pathologic hallmark of NMO.…”