“…MS patients show a wide variety of neurological symptoms, including paresthesia or numbness, motor weakness, incoordination, gait disturbance, and cognitive impairment (Cree, 2014; Miller and Leary, 2007; Milo and Miller, 2014). As seen in humans, certain behavioral changes can be observed in EAE mice (Acharjee et al, 2013; Franco-Pons et al, 2007; Jones et al, 2008; Legroux and Arbour, 2015; Moore et al, 2014; Serra-de-Oliveira et al, 2015; Ulrich et al, 2010; Wang et al, 2013).…”