Progressive myopia due to posterior staphyloma in type I osteogenesis imperfecta

Scott, Andrew; Kashani, Shahram; Towler, Hamish M. A.

doi:10.1007/s10792-006-9012-y

Cited by 20 publications

(13 citation statements)

References 4 publications

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“…[3] The development of CNV in the patient reported here can be attributed to spontaneous ruptures in the retinal pigment epithelium (RPE)-Bruch's membrane–choriocapillaris complex, secondary to eyeball elongation in highly myopic eyes. [4] The 65-nm striated collagen fibrils of the inner and outer collagenous layers of the Bruch's membrane contain types I, III, and V and the choriocapillaris basement membrane contains collagen type IV.…”

Section: Discussionmentioning

confidence: 99%

Intravitreal bevacizumab for treatment of choroidal neovascularization associated with osteogenesis imperfecta

Rishi

Venkatraman

2012

Indian J Ophthalmol

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A 12-year-old girl, diagnosed of osteogenesis imperfecta, presented with sudden visual loss in the left eye. Investigations revealed an active choroidal neovascular membrane. She underwent treatment with intravitreal Bevacizumab (1.25 mg/0.05 ml). Follow-up at 1 month revealed the development of lacquer crack running through the macula, underlying the fovea. The patient received two re-treatments at 1-month intervals, following which the choroidal neovascularization (CNV) regressed completely. However, further progression of lacquer cracks was noted. At the last follow-up, 6 months following the last injection, the fundus remained stable and vision was maintained at 20/200. Considering the natural history of the disease and the increased risk of rupture of the Bruch's membrane in such eyes, the possible complication of a lacquer crack developing must be borne in mind, before initiating treatment.

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Section: Discussionmentioning

confidence: 99%

Intravitreal bevacizumab for treatment of choroidal neovascularization associated with osteogenesis imperfecta

Rishi

Venkatraman

2012

Indian J Ophthalmol

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“…Both the sclera and the cornea are 25% to 50% thinner compared with their counterparts in individuals without OI, possibly accounting for occasional reports of globe rupture with mild trauma. 7,8 Many other manifestations of OI, such as retinal detachment, cataracts, posterior embryotoxon, glaucoma, optic atrophy, and corneal ectasia, in the form of megalocornea and keratoconus appear less frequently in the literature. [8][9][10][11] The etiology of corneal ectasia in OI is unclear.…”

Section: Discussionmentioning

confidence: 99%

“…7,8 Many other manifestations of OI, such as retinal detachment, cataracts, posterior embryotoxon, glaucoma, optic atrophy, and corneal ectasia, in the form of megalocornea and keratoconus appear less frequently in the literature. [8][9][10][11] The etiology of corneal ectasia in OI is unclear. Mechanistically, it would be logical to assume that cornea ectasia would be the consequence of defective corneal collagen formation along with thinning.…”

Section: Discussionmentioning

confidence: 99%

Descemet Stripping Automated Endothelial Keratoplasty for Spontaneous Descemet Membrane Detachment in a Patient With Osteogenesis Imperfecta

Gorovoy

Ullman

et al. 2012

Cornea

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“…Vértebras osteoporóticas não apresentam resistência suficiente para suportar as forças tênseis do peso corpóreo, o que resulta em alterações posturais da cabeça e pescoço, escoliose e outras deformidades da coluna 2 . Fraturas frequentes ocasionam dor, deformidades e inabilidades, enquanto que alterações na córnea e esclera podem levar a distúrbios visuais 13 . A possibilidade de serem portadores de doenças cardio-vasculares 5 exige uma avaliação odontológica pré-operatória mais criteriosa, além de antibioticoterapia profilática na ocorrência de defeitos valvulares.…”

Section: Discussionunclassified

Características Clínicas e Radiográficas da Osteogênese Imperfeita Associada à Dentinogênese Imperfeita

Kanno¹,

Oliveira²

2009

Odonto

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RESUMO A osteogênese imperfeita é uma doença hereditária que afeta tecido conjuntivo. Pode ser classificada em sete tipos, conforme as características clínicas, radiográficas, histológicas e genéticas, e subtipos, conforme a presença ou não de dentinogênese imperfeita. O objetivo do presente trabalho é apresentar um caso familiar de osteogênese imperfeita do tipo IV associada à dentinogênese imperfeita. A paciente apresentava deficiência de crescimento corpóreo e história de várias fraturas ósseas. Os dentes tinham a coloração marrom, com baixa incidência de cárie, embora pudessem ser observados desgastes de suas faces incisais ou oclusais. Aos exames radiográficos panorâmico e periapical, observou-se que as câmaras pulpares e canais radiculares eram amplos nos dentes em formação ou recém-erupcionados, mas obliterados naqueles totalmente irrompidos. Através do levantamento da história familiar constatou-se que o pai também era portador de osteogênese imperfeita, diagnosticada apenas após a quarta fratura de fêmur, com associação à dentinogênese imperfeita. Características semelhantes descritas nesse trabalho foram também observadas em uma irmã mais jovem. Palavras-chave: Osteogênese Imperfeita; Dentinogênese Imperfeita; Colágeno Tipo I.

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Progressive myopia due to posterior staphyloma in type I osteogenesis imperfecta

Cited by 20 publications

References 4 publications

Intravitreal bevacizumab for treatment of choroidal neovascularization associated with osteogenesis imperfecta

Intravitreal bevacizumab for treatment of choroidal neovascularization associated with osteogenesis imperfecta

Descemet Stripping Automated Endothelial Keratoplasty for Spontaneous Descemet Membrane Detachment in a Patient With Osteogenesis Imperfecta

Características Clínicas e Radiográficas da Osteogênese Imperfeita Associada à Dentinogênese Imperfeita

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