Abstract:JC polyomavirus (JCV) establishes an asymptomatic latent and/or persistent infection in most of the adult population. However, in immunocompromised individuals, JCV can cause a symptomatic infection of the brain, foremost progressive multifocal leukoencephalopathy (PML). In the last two decades, there has been increasing concern among patients and the medical community as PML was observed as an adverse event in individuals treated with modern (selective) immune suppressive treatments for various immune-mediate… Show more
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