Progressive late‐onset porokeratotic eccrine ostial and dermal duct naevus

Generalized, Linear Hyperkeratotic Papules With Numerous White Spicules and Comedo-like Plugs

“…1 Porokeratotic eccrine ostial and dermal duct nevus usually appears at birth or in early childhood, although late-onset presentations have also been reported. 2 Clinical features of PEODDN include multiple, asymptomatic, or mildly pruritic white-to-brown papules or plaques comprising punctate pits and comedo-like plugs, with a predilection for extremities with a linear distribution along Blaschko lines. 2 Generalized lesions with numerous white spicules, as with this patient, are rare.…”

“…2 Clinical features of PEODDN include multiple, asymptomatic, or mildly pruritic white-to-brown papules or plaques comprising punctate pits and comedo-like plugs, with a predilection for extremities with a linear distribution along Blaschko lines. 2 Generalized lesions with numerous white spicules, as with this patient, are rare. Other diseases and PEODDN may coexist, such as seizures, left hemiparesis and scoliosis, deafness and developmental delay, palmoplantar keratoderma, psoriasis, hyperthyroidism and polyneuropathy, breast hypoplasia, and keratitisichthyosis-deafness syndrome.…”