Progress in Probe-Based Sensing Techniques for In Vivo Diagnosis

Cheng, Zhenmin; Lin, Zijia; Huang, Shaoping; Li, Bing; Gao, Anzhu

doi:10.3390/bios12110943

Cited by 3 publications

(2 citation statements)

References 101 publications

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“…OCT can provide more detailed information about the loss of the optic nerve head and neurons quantitatively. However, in the early stages of glaucoma it is difficult to detect neuronal injuries, which would be permanent (Shao et al, 2022 ; Zhou et al, 2022 ). Therefore, early diagnosis and intervention to delay the progress of glaucoma and achieve a better prognosis are urgently needed.…”

Section: Discussionmentioning

confidence: 99%

A bibliometric analysis of apoptosis in glaucoma

Zhang

Wang²,

Tan³

et al. 2023

Front. Neurosci.

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BackgroundGlaucoma is the first irreversible and second blindness disease, which is characterized by the death of retinal ganglion cells (RGCs) and degeneration of the optic nerve. Previous works have indicated that apoptosis is the main reason for RGC death in glaucoma. Although many studies have investigated the mechanism of apoptosis and different strategies targeting apoptosis to protect the RGCs and finally recover the impaired vision in the glaucoma. However, the global trend and hotspots of apoptosis in glaucoma have not been well illustrated and discussed.MethodsDocuments were extracted from the Web of Science Core Collection on November 2, 2022. We selected articles and reviews published in English from January 1, 1999 to November 1, 2022 to perform visual analysis and statistical analysis of countries, institutions, authors, references and keywords by VOSviewer 1.6.18 and CiteSpace 5.8.ResultsThe publications about apoptosis in glaucoma show an increasing trend over time. Besides, the authors, institutions in the US and China published the most numbers of articles with the highest citation, which may be leading the research in the field of apoptosis in glaucoma. Last, series of advanced research results, technology and treatment for glaucoma, such as the discovery of key regulatory mechanisms on RGC apoptosis are emerging and will provide precise strategies for the treatment of glaucoma.ConclusionThis research will broaden our comprehension about the role of apoptosis in the process of glaucoma, and provide guidelines for us in basic research and disease treatment in the further.

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Section: Discussionmentioning

confidence: 99%

A bibliometric analysis of apoptosis in glaucoma

Zhang

Wang²,

Tan³

et al. 2023

Front. Neurosci.

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“…[2,3] Moreover, telemedicine allows knowledge sharing between different clinicians online, even for incidentally training younger mentors. Since robots for surgery have a unique advantage, robot-assisted telemedicine has gained increasing attention in recent years, [4][5][6][7][8] such as the RAVEN surgical robot system-assisted remote telesurgery. [8] In robot-assisted telemedicine, the user is endowed with full control of the remote robot through cooperation between a human operator and the remotely controlled robot.…”

mentioning

confidence: 99%

Robotic Manipulator‐Assisted Omnidirectional Augmented Reality for Endoluminal Intervention Telepresence

Lin,

Xu,

Liu

et al. 2023

Advanced Intelligent Systems

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Robotic telemedicine can provide timely treatment to critical patients in geographically remote locations. However, owing to the lack of depth information, occlusion of instrument, and view direction limitations, visual feedback from the patient to the clinician is typically unintuitive, which affects surgical safety. Herein, an omnidirectional augmented reality (AR)‐assisted robotic telepresence for interventional medicine is developed. A monocular camera is used as an AR device with a manipulator, where virtual key anatomies and instruments are superimposed on video images using multiobject hand–eye calibration, iterative closest point, and images superposition algorithms. The view direction of the camera can be changed via the manipulator, which allows the key anatomies and instruments to be viewed from different directions. Structure‐from‐motion and multi‐view stereo algorithms are used to reconstruct the scene on the patient's side, thus providing a virtual reality (VR) interactive interface for the manipulator's safe teleoperation. Two different phantom experiments are conducted to validate the effectiveness of the proposed method. Finally, an ex vivo experiment involving a porcine lumen is performed, in which the operator can view the interventional flexible robot. The proposed method integrates omnidirectional AR and VR with robotic telepresence, which can provide intuitive visual feedback to clinicians.

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