Progress and Perspective of Antiviral Protective Material

Zhou, Jialiang; Hu, Zexu; Zabihi, Fatemeh; Chen, Zhigang; Zhu, Meifang

doi:10.1007/s42765-020-00047-7

Cited by 164 publications

(124 citation statements)

References 67 publications

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“…Moreover, the impregnating/coating of classical antibacterial metals/metal oxides in nano/micro size scales, such as copper oxide, zinc oxides, titanium oxide, silver oxide etc. onto disposable N95 respiratory mask layers, showed that the mask layers had an anti-viral activity against human influenza A virus (H1N1) and avian influenza virus (H9N2) [ 65 , 66 ]. These metals and metallic oxides could be useful in integrating anti-viral activity onto the surfaces of masks and other PPE to reduce the risk of infection and environmental contamination, with novel coronavirus, for COVID-19.…”

Section: Coatings Empowering Antiviral and Viricidal Propertiesmentioning

confidence: 99%

Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics

et al. 2020

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The worldwide, extraordinary outbreak of coronavirus pandemic (i.e., COVID-19) and other emerging viral expansions have drawn particular interest to the design and development of novel antiviral, and viricidal, agents, with a broad-spectrum of antiviral activity. The current indispensable challenge lies in the development of universal virus repudiation systems that are reusable, and capable of inactivating pathogens, thus reducing risk of infection and transmission. In this review, science-based methods, mechanisms, and procedures, which are implemented in obtaining resultant antiviral coated substrates, used in the destruction of the strains of the different viruses, are reviewed. The constituent antiviral members are classified into a few broad groups, such as polymeric materials, metal ions/metal oxides, and functional nanomaterials, based on the type of materials used at the virus contamination sites. The action mode against enveloped viruses was depicted to vindicate the antiviral mechanism. We also disclose hypothesized strategies for development of a universal and reusable virus deactivation system against the emerging COVID-19. In the surge of the current, alarming scenario of SARS-CoV-2 infections, there is a great necessity for developing highly-innovative antiviral agents to work against the viruses. We hypothesize that some of the antiviral coatings discussed here could exert an inhibitive effect on COVID-19, indicated by the results that the coatings succeeded in obtaining against other enveloped viruses. Consequently, the coatings need to be tested and authenticated, to fabricate a wide range of coated antiviral products such as masks, gowns, surgical drapes, textiles, high-touch surfaces, and other personal protective equipment, aimed at extrication from the COVID-19 pandemic.

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Section: Coatings Empowering Antiviral and Viricidal Propertiesmentioning

confidence: 99%

Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics

et al. 2020

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“…Attacking the ions of CuO NPs to the COVID -19 virus's membrane, and destroying the virus' DNA structure can be also supportive findings for NP's antiviral effects [14,15].…”

Section: (E) Drug Nanoformulation Development Against Coronavirusmentioning

confidence: 69%

“…These two sets consist the oxidant part of the nanoformulation drug. On the other hand, attacking to the virus membrane, and destroying the virus' DNA structure, can also be found in CuO NPs researches [14,15].…”

Section: (E) Drug Nanoformulation Development Against Coronavirusmentioning

confidence: 99%

The Mirror Strategy of Nanoparticles against the Coronavirus

Fakhroueian¹

2020

Preprint

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Research on the chemical mechanism and reciprocal behavior of the coronavirus relate to living organisms, engaging in the give and take of electrochemical mediators, is a very important, controversial and vital issue. What we should accept is the chemical identity of this scenario, and not preferably a characteristic of a biological system. This chemical reaction should be familiar, going back to the theory of chemical pathways involved in DNA/proteins in the body against aggressive guests (such as viruses). From the point of view of a chemist, this simple reaction is nothing more than an oxidation-reduction reaction (redox-stress signaling) which conducted and carried out by coronavirus in a biointerface medium. Thereby, oxidizing as well as reducing reagents should be very constructive, promoting development in such chemical process. We understand redox reactions as switchable thiol/disulfide exchanges (formation and cleavage of inherent disulfide bonds), thereby, we can hugely profit from redox-responsive nano-surfaces equipped with multiple new ionic and covalent interactions. This game-changing idea can substantiate by surface modified-nanoparticles to play powerful roles in synthesis of nano oxidizers as well as reducing agents in nanomedicine. Chemists and pharmacists must then explore new thoughts and present modern experiences/approaches of preparation nanoparticles and nanocomposites to create novel vaccines as well as coronavirus drugs. In this regard, this experience can also be so helpful for HIV/AIDS, which is caused by viruses.

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“… 49 A recent review has summarized the advances in antiviral materials and their mechanisms of activity, and it highlighted that nanomaterials, including metal-based, carbon-based, silicon-based, organic-based, and intrinsic antiviral materials, should be studied to improve the antiviral capability of PPE (e.g., filtering materials for face masks). 50 In addition, an emerging strategy to treat microbial infection is to create cell-membrane mimics as decoys to trap and detain the pathogens, 51 which gives the chance to inactivate the viruses/bacteria while retaining immunogenicity. However, the active-loaded and protein-coated products currently available have limitations for long-term use, as they deplete or degrade over time.…”

Section: Introductionmentioning

confidence: 99%

All Surfaces Are Not Equal in Contact Transmission of SARS-CoV-2

Xue

Ball

Ghaemmaghami

et al. 2020

Matter

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The world faces a severe and acute public health emergency due to the ongoing coronavirus disease 2019 (COVID-19) global pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Healthcare workers are in the front line of the COVID-19 outbreak response and are exposed to the risk of SARS-CoV-2 infection daily. Personal protective equipment (PPE) is their main defense against viral contamination; gloves, visors, face masks, and gown materials are designed to eliminate viral transfer from infected patients. Here, we review research investigating the stability of SARS-CoV-2 and similar viruses on surfaces and highlight opportunities for materials that can actively reduce SARS-CoV-2 surface contamination and associated transmission and improve PPE.

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Progress and Perspective of Antiviral Protective Material

Cited by 164 publications

References 67 publications

Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics

Science-Based Strategies of Antiviral Coatings with Viricidal Properties for the COVID-19 Like Pandemics

The Mirror Strategy of Nanoparticles against the Coronavirus

All Surfaces Are Not Equal in Contact Transmission of SARS-CoV-2

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