Prognostic value of echocardiography after acute myocardial infarction

Mollema, Sjoerd A.; Nucifora, Gaetano; Bax, Jeroen J.

doi:10.1136/hrt.2008.161836

Cited by 73 publications

(52 citation statements)

References 90 publications

(96 reference statements)

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“…39 Furthermore, the diagnosis of ventricular remodelling is mainly based on the echocardiographic evaluation at follow-up. Our results revealed that initial decrease of LVEF and enlarged end-systolic volume may predict LV remodelling.…”

Section: Discussionmentioning

confidence: 99%

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Left ventricular remodelling after acute myocardial infarction: Impact of clinical, echocardiographic parameters and polymorphism of angiotensinogen gene

Žaliaduonytė-Pekšienė

Šimonytė

Lesauskaitė

et al. 2013

J Renin Angiotensin Aldosterone Syst

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Introduction: The development of left ventricular remodelling after acute myocardial infarction is a predictor of heart failure and mortality. The purpose of the present study was to assess whether the polymorphism of angiotensinogen (AGT) gene with threonine (T) instead of methionine (M) at amino acid 235 in exon 2 (M235T) had effects on cardiac remodelling after acute myocardial infarction. Methods: One hundred and forty-one patients (mean age 56.4±11.1 years) with a first acute myocardial infarction were enrolled. Within 24-72 hours of the onset of the symptoms and at a four month period two-dimensional echocardiography was performed. Remodelling was defined as a 20% increase from the baseline in left ventricular end-diastolic volume. The genotypes of the study group were compared with the reference group (n=1010) genotypes. AGT M235T polymorphism was determined using polymerase chain reaction amplification. Results: At follow-up, 49 patients (34.7%) were classified as having left ventricular remodelling. Anterior localization of the infarct (p=0.008), leucocyte count at admission (p=0.040), global left ventricular longitudinal strain (p=0.021) and MM genotype of AGT (p=0.024) were independent predictors of ventricular remodelling after myocardial infarction. Conclusions: Anterior wall infarction, increased leucocyte count, decreased longitudinal strain of left ventricular and polymorphism of AGT M235T may predict remodelling after myocardial infarction.

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Section: Discussionmentioning

confidence: 99%

“…The diagnostic reliability of longitudinal strain is still under evaluation and it has been reported as a novel sensitive diagnostic echocardiographic parameter in some studies, while showing no exceptional importance in the others. 18,19,39,40 …”

Section: Discussionmentioning

confidence: 99%

Left ventricular remodelling after acute myocardial infarction: Impact of clinical, echocardiographic parameters and polymorphism of angiotensinogen gene

Žaliaduonytė-Pekšienė

Šimonytė

Lesauskaitė

et al. 2013

J Renin Angiotensin Aldosterone Syst

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“…[3][4][5][6][7] However, the assessment of LVEF and WMSI has several limitations. The measurement of LVEF with 2D echocardiography is based on geometric assumptions used to calculate LV volumes.…”

Section: Gls Versus Lvef and Wmsimentioning

confidence: 99%

“…1,2 In patients with chronic ischemic cardiomyopathy, left ventricular (LV) ejection fraction (EF), and wall motion score index (WMSI) are well-established predictors of long-term outcome. [3][4][5][6][7] However, both LVEF and WMSI have some limitations related to reproducibility, geometric assumption, and expertise.…”

mentioning

confidence: 99%

Global Longitudinal Strain Predicts Long-Term Survival in Patients With Chronic Ischemic Cardiomyopathy

Bertini

Antoni

et al. 2012

Circ: Cardiovascular Imaging

149

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Background-Left ventricular (LV) global longitudinal strain (GLS) is a measure of the active shortening of the LV in the longitudinal direction, which can be assessed with speckle-tracking echocardiography. The aims of this evaluation were to validate the prognostic value of GLS as a new index of LV systolic function in a large cohort of patients with chronic ischemic cardiomyopathy and to determine the incremental value of GLS to predict long-term outcome over other strong and well-established prognostic factors. Methods and Results-A total of 1060 patients underwent baseline clinical evaluation and transthoracic echocardiography.Median age was 66.9 years (interquartile range, 58.4, 74.2 years); 739 (70%) were men. The median follow-up duration for the entire patient population was 31 months. During the follow-up, 270 patients died and 309 patients reached the combined end point (all-cause mortality and heart failure hospitalization). Compared with survivors, patients who died (270, [25%]) had larger LV volumes (PϽ0.05), lower LV ejection fraction (Pϭ0.004), higher wall motion score index (Pϭ0.001), and greater impairment of LV GLS (PϽ0.001). After dichotomizing the population on the basis of the median value of LV GLS (Ϫ11.5%), patients with an LV GLS ՅϪ11.5% had superior outcome compared with patients with an LV GLS ϾϪ11.5% (log-rank

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“…19 Previous studies with patients with AMI had used initial CFR as a predictor of ventricular wall motion recovery by observing follow-up regional wall motion changes with the echocardiogram. 20 This study demonstrated CFR as a marker in evaluation of left ventricular recovery in patients with AMI. The improvement in left ventricular ejection fraction measured by echocardiogram in this study was not significant, but improvement of CFR measurements was significant, implying that a subtle improvement in left ventricular function could not be differentiated from the use of a conventional echocardiogram.…”

Section: Discussionmentioning

confidence: 61%

Correlation Between Circulating Angiogenic Cell Mobilizations and Recovery of Coronary Flow Reserve in Patients With Acute Myocardial Infarction

Jeong

Hong

Park

et al. 2012

Circ J

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Prognostic value of echocardiography after acute myocardial infarction

Cited by 73 publications

References 90 publications

Left ventricular remodelling after acute myocardial infarction: Impact of clinical, echocardiographic parameters and polymorphism of angiotensinogen gene

Left ventricular remodelling after acute myocardial infarction: Impact of clinical, echocardiographic parameters and polymorphism of angiotensinogen gene

Global Longitudinal Strain Predicts Long-Term Survival in Patients With Chronic Ischemic Cardiomyopathy

Correlation Between Circulating Angiogenic Cell Mobilizations and Recovery of Coronary Flow Reserve in Patients With Acute Myocardial Infarction

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