Correlation Between Circulating Angiogenic Cell Mobilizations and Recovery of Coronary Flow Reserve in Patients With Acute Myocardial Infarction

Jeong, Han Saem; Hong, Soon Jun; Park, Jae Hyoung; Kim, Jong Ho; Choi, Seung Cheol; Ahn, Chul Min; Kim, Je Sang; Lim, Do Sun

doi:10.1253/circj.cj-11-1485

Cited by 6 publications

(1 citation statement)

References 35 publications

(31 reference statements)

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“…CFR has also been shown to correlate to markers of low degree systemic inflammation, such as C-reactive protein [39] and neutrophil count [40]. Based on large-scale genetic association studies, IL-6 has recently been shown to be causally linked to CV outcome alongside LDL-regulating pathways [41].…”

Section: Determinants Of Cfr In Manmentioning

confidence: 99%

Coronary Flow Reserve from Mouse to Man—from Mechanistic Understanding to Future Interventions

Gan

Wikström

Fritsche‐Danielson

2013

J. of Cardiovasc. Trans. Res.

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Myocardial ischemia is recognized as an important mechanism increasing the risk for cardiovascular events in both symptomatic and asymptomatic patients. In addition to obstructive coronary diseases, systemic inflammation, macro- and microvascular function are additional important mechanisms contributing to the ischemic myocardium. Accumulating evidence indicates that coronary flow reserve (CFR) is a quantitative measurement of ischemia including integrated information on structure and function of the coronary artery at all levels. Not surprisingly, CFR has been shown to confer strong prognostic value for hard cardiovascular (CV) events in a number of relevant patient cohorts. Using high-resolution imaging, it is now possible to study coronary arteries from mouse to man. Therefore, CFR may be an important translational tool to risk-stratify patients and to perform both preclinical and clinical proof-of-concept studies before investing in large-scale outcome trials, thus improving the translational value for novel CV targets.

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Section: Determinants Of Cfr In Manmentioning

confidence: 99%

Coronary Flow Reserve from Mouse to Man—from Mechanistic Understanding to Future Interventions

Gan

Wikström

Fritsche‐Danielson

2013

J. of Cardiovasc. Trans. Res.

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Comparison of Ticagrelor Versus Prasugrel for Inflammation, Vascular Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non–ST-Segment Elevation Acute Coronary Syndrome Requiring Coronary Stenting

Jeong

Hong

Cho

et al. 2017

JACC: Cardiovascular Interventions

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Compared with prasugrel, ticagrelor significantly decreased inflammatory cytokines such as interleukin 6 and tumor necrosis factor alpha and increased circulating EPCs, contributing to improved arterial endothelial function in diabetic non-ST-segment elevation acute coronary syndrome patients. Thus, data support that pleiotropic effects of ticagrelor beyond its potent antiplatelet effects could contribute to additional clinical benefits. (Comparison of Ticagrelor vs. Prasugrel on Inflammation, Arterial Stiffness, Endothelial Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non-ST Elevation Acute Coronary Syndrome [NSTE-ACS] Requiring Coronary Stenting; NCT02487732).

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Coronary Flow Reserve and Ventricular Function Following Regenerative Treatment in Patients With Revascularized Acute Anterior Myocardial Infarction

Garzón

Álvarez‐Ossorio

Moreno

et al. 2018

Revista Española de Cardiología (English Edition)

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Correlation Between Circulating Angiogenic Cell Mobilizations and Recovery of Coronary Flow Reserve in Patients With Acute Myocardial Infarction

Cited by 6 publications

References 35 publications

Coronary Flow Reserve from Mouse to Man—from Mechanistic Understanding to Future Interventions

Coronary Flow Reserve from Mouse to Man—from Mechanistic Understanding to Future Interventions

Comparison of Ticagrelor Versus Prasugrel for Inflammation, Vascular Function, and Circulating Endothelial Progenitor Cells in Diabetic Patients With Non–ST-Segment Elevation Acute Coronary Syndrome Requiring Coronary Stenting

Coronary Flow Reserve and Ventricular Function Following Regenerative Treatment in Patients With Revascularized Acute Anterior Myocardial Infarction

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