Prognostic value of biventricular mechanical parameters assessed using cardiac magnetic resonance feature‐tracking analysis to predict future cardiac events

Abstract

3 J. Magn. Reson. Imaging 2017;45:1034-1045.

MRI feature tracking strain is prognostic for all-cause mortality in AL amyloidosis

“…This study also adds to the MRI FT strain prognostic literature, which has grown rapidly in large part due to the ability to retrospectively measure MRI FT strain from b-SSFP images. MRI FT strain parameters at baseline have been shown to predict outcomes in Tetralogy of Fallot in 372 patients with a median follow-up of 7.4 years [12], dilated cardiomyopathy in 210 patients with a median follow-up of 5.3 years [13], hypertrophic cardiomyopathy in 30 patients with a median follow-up of [14], a mixed cohort of 364 patients with a variety of cardiac conditions for a median follow-up of 15 months [15]. In contrast, MRI tagging was first described in 1988 [5], but because tagging requires special prospective acquisitions, it was not until 2009 that a paper from the Multi-Study of Atherosclerosis (MESA) study showed the association of baseline MRI tagging strain with outcomes in a large population of 1099 subjects [20].…”

“…In 210 patients with dilated cardiomyopathy, Buss et al [13] prospectively found that global longitudinal strain remained prognostic when combined with BNP, LV ejection fraction and mass of delayed enhancement ( p <.02). In 364 patients with ischemic heart disease, cardiomyopathies, valvular heart disease and congenital heart disease, Yang et al [15] retrospectively found that global transverse strain (radial strain measured from long axis images) remained prognostic when combined with age, sex and LV ejection fraction ( p =.04).…”

“…However, while several other cardiac MRI parameters have been shown to be prognostic in amyloidosis, including delayed enhancement [9,10], native T1 mapping and extracellular volume [11], and while MRI FT strain has been shown to be prognostic in other cardiac conditions [12–15], to date the prognostic significance of MRI FT strain has not been shown in amyloidosis. Therefore, the purpose of this study was to retrospectively evaluate the prognostic value of MRI FT strain for determining all-cause mortality in AL amyloidosis.…”

Global Left Ventricular Area Strain Using Standard Two-Dimensional Cine Magnetic Resonance Imaging with Inter-Slice Interpolation

“…Feature tracking magnetic resonance imaging (FT-MRI) allows tracking of tissue voxel motion using only the standard twodimensional (2D) cine MRI and can be used to evaluate wall mechanics and strains without acquisition of additional sequences [1]. FT-MRI has been validated against myocardial tagging with harmonic phase imaging [2], and the usefulness of strain value as a clinical indicator [3][4][5][6][7]. However, FT-MRI has the intrinsic limitation of being 2D.…”

Prognostic Value of Left Ventricular Function and Mechanics in Pulmonary Hypertension: A Pilot Cardiovascular Magnetic Resonance Feature Tracking Study

“…In the last few decades, additional technologies have appeared, so the evaluation of the heart has expanded from being structural/functional to mechanical in nature. Echocardiographic speckle tracking, the first modality used for tissue tracking in cardiac imaging [12], revealed that not only volumetric, but also mechanical evaluation of the ventricles can be performed in patients with cardiovascular and pulmonary pathology [13,14,15,16,17,18], and may be useful in taking different clinical decisions. Since echocardiography images have a lower signal-to-noise ratio than CMR and are highly dependent on the image quality (operator dependence, patient body habitus (echo window)) [19], feature tracking (FT) has become a more attractive technology for the evaluation of myocardial deformation.…”