Prognostic significance of dynamic inflammatory indexes in cases renal cell cancer treated by tyrosine kinase inhibitor (TKI)

Mirili, Cem; Paydaş, Semra; Yılmaz, Ali Faik; Oğul, Ali; Büyükşimşek, Mahmut; Yetisir, Abdullah Evren; Tohumcuoglu, Mert

doi:10.5505/aot.2019.08760

Cited by 1 publication

(2 citation statements)

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“…On the other hand, deciding PLR as critical marker within the XFS proposes that PLR can be utilized as a discriminant marker in exfoliative spectrum without glaucomatous damage (XFS phase). Currently, SII is recommended for predicting the prognosis of systemic inflammatory diseases and malignancies [6][7][8] . There is a limited number of studies investigating the association between SII and ocular diseases such as glaucoma in the literature.…”

Section: Discussionmentioning

confidence: 99%

“…indicators of systemic inflammatory conditions obtained from peripheral venous sampling, including the neutrophil / lymphocyte ratio (NLR), platelet / lymphocyte ratio (PLR), lymphocyte / monocyte ratio (LMR), serum lipid levels, and the systemic immune inflammation index (SII), have been proposed as prognostic indicators in several inflammatory disorders and malignancies [1][2][3][4][5][6][7][8][9] .…”

Section: Hematologicalmentioning

confidence: 99%

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Comparison of hematological inflammatory parameters in patients with exfoliative glaucoma and exfoliative syndrome

Demirtaş¹,

Karahan²

2021

Dicle Tıp Dergisi

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Objective: To evaluate the neutrophil / lymphocyte ratio (NLR), platelet / lymphocyte ratio (PLR), and systemic immune inflammation index (SII) in exfoliative glaucoma (XFG) patients with the aim of comparing the findings with those of healthy controls and exfoliative syndrome (XFS) patients. Methods:In this retrospective cross-sectional study included 134 participants, 22 XFG patients, 41 XFS patients and 71 healthy individuals were examined. Peripheral venous sample values including neutrophil, lymphocyte and platelet levels were recorded from the hospital database.Results: Among evaluated hematological parameters, although the NLR values of the subjects with XFG were greater than those of the subjects with XFS, when the relationship between the NLR, PLR and SII parameters of the XFG and XFS groups, adjusted for age and gender, was examined by logistic regression analysis, no significant difference was found between the groups. Multiple linear regressions of the association between the NLR, PLR and SII parameters and the ocular parameters of the XFG and XFS groups revealed no significant relationship between the blood parameters and ocular measurements. Neutrophil / lymphocyte ratio was found to be the most acceptable discriminant parameter when comparing XFG group with the XFS and control groups (AUC [area under curve]=0.678, AUC=0.663, respectively). Platelet / lymphocyte ratio was found to be the best discriminant parameter between the XFS and control groups (AUC=0.605). Conclusion:No significant difference was found between XFG and XFS groups in terms of NLR, PLR and SII parameters. Considering the fact that NLR has the best AUC when comparing XFG and XFS groups, it may be the most acceptable discriminant parameter between XFG and XFS.

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Section: Discussionmentioning

confidence: 99%