Prognostic significance of cortical perforation in the recurrence of central giant cell granulomas of the jaws

Long-term clinical and radiological outcomes of surgical management of central giant cell granuloma of the maxilla

“…In this study, it was found that 75% of patients with maxillary CGCG were below 30 years of age with a female predominance (58.3%), which is similar to the findings of other investigators 9,15,18,26,33,35 . The anatomic distribution of CGCG of the maxilla reported in other published studies shows a predilection (62.5%) for the anterior maxilla with a right side preponderance 1,7,9,11,15,18,20,26,28,35 .…”

“…CGCG of the mandible is a welldescribed clinical entity 5,9,10,18,26,35 . However, information on the maxillary lesion in published studies is scarce: there have been no large series reported to specifically document the clinical and radiographic features, management, and results following surgery for this lesion.…”

A case of aggressive multiple metachronous central giant cell granulomas of the jaws: differential diagnosis and management options

“…Generally, curettage of well-defined localized lesions is associated with a low rate of recurrence 10 . Non-aggressive lesions which do not recur, tend to have smaller, irregularly shaped and unevenly distributed giant cells, form osteoid and the lesional cells have fewer mitoses 6,10 . In extensive lesions with radiographic or histological evidence of perforation of the cortex, a more radical excision has been advocated 6 .…”

Central giant cell granuloma in anterior maxilla

“…It has been reported that recurrence is usually found when the lesion perforates the cortical plates to involve the surrounding soft tissue. 9 There have been reports of recurrence as early as 3 years and as late as 22 years. 10 Radiologic features vary from undefined destructive lesions to a well-defined, multilocular appearance.…”