Long-term clinical and radiological outcomes of surgical management of central giant cell granuloma of the maxilla

“…Patients typically present with painless, progressive swelling of the face [35] . Central giant cell granuloma of the maxilla is generally located anteriorly and has a higher likelihood of expansion causing cortical thinning and destruction [36] . It can be differentiated into two categories, aggressive and nonaggressive, on the basis of symptoms, radiographic findings, and number of giant cells on histopathologic study [36] .…”

Section: Benign Reactive Bone Lesions Of the Orbitmentioning

confidence: 99%

“…Central giant cell granuloma of the maxilla is generally located anteriorly and has a higher likelihood of expansion causing cortical thinning and destruction [36] . It can be differentiated into two categories, aggressive and nonaggressive, on the basis of symptoms, radiographic findings, and number of giant cells on histopathologic study [36] . Aggressive lesions are more likely to present with faster growth and destruction of adjacent structures, have a greater tendency to recur, and have increased vascular density, which makes them more responsive to antiangiogenic therapy [37] .…”

Section: Benign Reactive Bone Lesions Of the Orbitmentioning

confidence: 99%

“…The advocated treatment is surgical excision with curettage; however, recurrence has been reported in 4-37% of cases [34][35][36]38] . In 1 case series, radical en bloc resection with wide local excision and with margins of 1 cm was employed in 18 locally aggressive cases characterized by large size, high growth rate, and severe pain, and there was only 1 (6%) recurrence during a mean follow-up time of 3.9 years [39] .…”

Section: Benign Reactive Bone Lesions Of the Orbitmentioning

confidence: 99%

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Treatment Challenges with Benign Bone Tumors of the Orbit

Merritt

Yin²,

Pfeiffer

et al. 2015

Ocul Oncol Pathol

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Benign mesenchymal tumors of the craniofacial complex present unique challenges for orbital surgeons because of their potential for orbital compartment syndrome, ocular morbidity, and facial disfigurement and because definitive surgical management may be associated with significant morbidity. While the precise classification of such lesions depends on radiologic as well as histologic evaluations and remains controversial, benign tumors involving the bony walls of the orbit share features of bony expansion, facial deformity, and the potential to cause significant orbital and ophthalmic morbidity. We herein present 2 cases of benign mesenchymal tumors with bony involvement in the orbitofacial region (1 juvenile ossifying fibroma and 1 central giant cell granuloma) and review the current management of similar benign fibro-osseous and reactive bone lesions of the orbit. These rare entities presented share common orbital and ophthalmic manifestations and remain without any effective definitive treatment options.

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“…World Health Organization defines central giant cell granuloma (CGCG) as an intraosseous lesion consisting of cellular fibrous tissue that contains multiple foci of hemorrhage, aggregations of multinucleated giant cells and occasional trabeculae of woven bone [2,3].…”

Section: Introductionmentioning

confidence: 99%

Midfacial Degloving Approach for Bilateral Giant Cell Reparative Granuloma

Ahluwalia

Morwani

2016

J Curr Surg

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Reparative giant cell granuloma is a rare benign tumor. Mandible is the most common site. The case is reported for its rarity in maxilla and difficulty in differentiating it from other giant cell lesions. Differentiation is only based on the clinical test and histopathological examination. Midfacial degloving approach popularized by Caisson et al and Conley in 1974 is best suited for bilateral facial lesions. This approach gives a wide exposure with no facial scar or deformity. The advantages of the degloving technique in exposure of the midface, maxilla, mandible, nasal cavities, and paranasal sinuses, have led to its increasing importance in the otorhinolaryngology.

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Long-term clinical and radiological outcomes of surgical management of central giant cell granuloma of the maxilla

Cited by 54 publications

References 35 publications

Giant Cell Lesion and Central Giant Cell Granuloma of Jaw: A Brief Review

Giant Cell Lesion and Central Giant Cell Granuloma of Jaw: A Brief Review

Treatment Challenges with Benign Bone Tumors of the Orbit

Midfacial Degloving Approach for Bilateral Giant Cell Reparative Granuloma

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