Prognostic indicators for toxic mastitis in dairy cows

Green, M. J.; Cripps, Peter; Green, L. E.

doi:10.1136/vr.143.5.127

Cited by 6 publications

(10 citation statements)

References 7 publications

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“…This was consistent with the result of Green et al [4] who found that there was a significant difference between the mean PCV of the cows which survived and those which died. Also, there were significant differences in rectal temperatures, eyelid skin tent time and packed cell volume between the cows which survived and those which died [4]. We found a positive relationship between the severity of systemic disease signs and the percentage of cows with an undesirable outcome (death or culling).…”

Section: Discussionsupporting

confidence: 83%

Classification of acute clinical mastitis on the base of vital signs and complete blood count test in dairy cows

Hur¹,

Kang²,

Jung³

et al. 2013

Korean Journal of Veterinary Research

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: This study was carried out to evaluate the diagnosis of acute clinical mastitis (ACM) which was based on the vital signs and complete blood count (CBC) tests in dairy cows. Twenty eight dairy cows diagnosed with ACM, were selected for the study between Jan 2003 and July 2006 in the National Institute of Animal Science. Based on their vital signs (rectal temperature, depression, rumen contraction and, dehydration status), ACM was divided into three different classes; mild, moderate and severe forms. In addition, ACM cows were subjected to CBC tests for further diagnosis of ACM. Of the 27 dairy cows diagnosed with ACM, 3 cows were determined to have a mild form, while moderate and sever forms were each observed in twelve cows. Among of them, 4 cows died, 5 cows were culled and 18 cows were recovered. In the mild form, all haematological parameters were comparable with normal values. However, leukopenia, due to neutropenia and lymphocytopenia, appeared characteristically in the moderate and severe forms. Using the observation of vital signs in conjunction with CBC tests, the diagnosis of ACM is more accurate, and is helpful in making decisions of whether treatment or culling of dairy cows infected with ACM is most appropriate.

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Section: Discussionsupporting

confidence: 83%

Classification of acute clinical mastitis on the base of vital signs and complete blood count test in dairy cows

Hur¹,

Kang²,

Jung³

et al. 2013

Korean Journal of Veterinary Research

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“…In light of our results, assessment of the local/systemic hypoperfusion is not of interest in the general population of DCS. This biomarker might be more useful when dealing with cases where hypoperfusion is well documented . The current study design and objectives did not allow us to test this hypothesis.…”

Section: Discussionmentioning

confidence: 93%

“…This biomarker might be more useful when dealing with cases where hypoperfusion is well documented. 42,43 The current study design and objectives did not allow us to test this hypothesis.…”

Section: Variablesmentioning

confidence: 93%

Prognostic Value of Cardiac Troponin I and L‐Lactate in Blood of Dairy Cows Affected by Downer Cow Syndrome

Labonté¹,

Dubuc

Roy

et al. 2017

Veterinary Internal Medicne

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BackgroundThe downer cow syndrome (DCS) is a challenging health issue in the dairy industry. No cow‐side test is available to provide an accurate prognosis for DCS cases in farm settings.Hypothesis/ObjectivesLocal or systemic hypoperfusion and myocardial lesions lead to an increase in blood concentration of biomarkers cardiac troponin I (cTnI) and L‐lactate. The objective was to determine the prognostic values of these biomarkers assessed cow‐sides in addition to clinical examinations in prognostication of a negative outcome (NO: death or euthanasia within 7 days).Animals218 client‐owned dairy cows affected by DCS.MethodsIn a prospective study, animals were monitored for 60 days after inclusion of each cow. Blood cTnI and L‐lactate concentrations were measured on the day of inclusion. The prognostic accuracy of both biomarkers and physical examination variables was estimated to predict NO. A mixed multivariable logistic regression model was used for data analysis.ResultsPrevalence of NO in this study was 63% on day 7. Troponin concentrations greater than 0.7 ng/mL had sensitivity and specificity of 54.1% (95% CI: 45.3–62.7%) and 78.4% (95% CI: 67.3–87.1%), respectively, for predicting NO. Blood L‐lactate was not associated with the outcome. The multivariable model revealed that heart rate >100 bpm (OR; 95% CI: 3.7; 1.3–10.2) and cTnI > 0.7 ng/mL (OR; 95% CI: 5.5; 2.1–14.6) were associated with the risk of NO.Conclusions and Clinical ImportanceHypertroponinemia and tachycardia were associated with reduced survival in DCS cases. The use of cow‐side blood cTnI concentrations and heart rate could help to rapidly identify cows in farm setting that have poor chances of recovery and would benefit from a more aggressive treatment or euthanasia.

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“…Despite the widespread occurrence of toxic mastitis, little quantitative information is available about the clinical and laboratory findings from such cases (Jones and Ward 1989, Katholm and Haubro Andersen 1992, Green and others 1998). This paper reports the results of clinical observations and laboratory analyses of samples obtained from cases of toxic mastitis in cows throughout Northern Ireland.…”

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confidence: 99%

Clinical and laboratory findings in cases of toxic mastitis in cows in Northern Ireland

Menzies¹,

McBride²,

McDowell³

et al. 2000

Veterinary Record

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This paper describes the clinical and laboratory findings from 264 cases of toxic mastitis in cows in Northern Ireland between October 1995 and May 1997. Nearly all the cases occurred during the winter housing period, with 84 per cent occurring between November and March inclusive, and 30 per cent in March. Sixty per cent of the cases occurred within one month of calving, and 29 per cent within four days of calving. The most common clinical signs were lethargy (92 per cent), discoloured milk (90 per cent), anorexia (72 per cent), tachypnoea (23 per cent), diarrhoea (23 per cent), recumbency (18 per cent) and staggering (15 per cent). Severe pyrexia (18 per cent) and clinical dehydration (44 per cent) were relatively common findings. Pure growths of Escherichia coli were isolated from 50 per cent of the milk samples, but 11 per cent yielded no bacterial growth. In vitro sensitivity tests indicated that enrofloxacin was effective against 98 per cent of the bacteria isolated, and framycetin and amoxycillin/clavulanic acid against 91 per cent. Abnormally high blood urea levels were observed in 31 per cent of cases, high blood creatinine levels in 42 per cent, and severe leucopenia in 56 per cent. Of the cases which were followed up, 14 per cent died, 21 per cent were culled early and a further 22 per cent lost milk production from the affected quarter.

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Prognostic indicators for toxic mastitis in dairy cows

Cited by 6 publications

References 7 publications

Classification of acute clinical mastitis on the base of vital signs and complete blood count test in dairy cows

Classification of acute clinical mastitis on the base of vital signs and complete blood count test in dairy cows

Prognostic Value of Cardiac Troponin I and L‐Lactate in Blood of Dairy Cows Affected by Downer Cow Syndrome

Clinical and laboratory findings in cases of toxic mastitis in cows in Northern Ireland

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