Prognostic factors in oocyte donation: an analysis through egg-sharing recipient pairs showing a discordant outcome

Effects of icariin on the expression of ER, VEGF, and KDR in the endometrial cells of thin endometrium

“…A thick endometrium is associated with a higher rate of successful pregnancy, live births, and ongoing pregnancy compared with women with thin endometria (Zhang et al, 2005). It is thought that a prerequisite of successful embryo implantation is the thickness of the endometrium: more than 6 mm and preferably 7-8 mm (Basir et al, 2002;Bodri et al, 2007). Therefore, a thicker endometrium aids a successful pregnancy.…”

Endometriosis and Implantation Failure: Review

“…Retrospektif çalışmalarda endometriyozlu hastalardan elde edilen oositlerde daha düşük implantasyon oranı dikkati çekerken, farklı sonuç-lar karşılaştırıldığında alıcıdaki endometriyoz sık-lığı açısından fark bulunamamıştır. 9,14,15 Prospektif çalışmalarda ise alıcıda endometriyozun olup olmaması gebelik oranlarını, implantasyon oranlarını, canlı doğum oranlarını etkilememiş gibi görünmektedir. 16,17 Bununla beraber donör oosit modellerinde endometriyozlu olgularda ötopik endometriyumun sorunsuz olduğuna dair çıkarım yanıltıcı olabilir.…”

What Is the Outcome and Fate of Frozen Supernumerary Embryos Resulting from Egg Donation?

“…Measurement of the uterine lining is often used as a noninvasive tool to assess uterine receptiveness; there have been several studies demonstrating that a thin endometrium (the de fi nition of which varies) is detrimental to embryo's ability to implant. While others have shown the correlation between thickness and success to be weak, measurement of the lining remains a universal component in the assessment of uterine suitability [6][7][8][9] . Although the majority of studies analyzing endometrial thickness and donor oocyte cycle outcome have been conducted in patients undergoing fresh donor cycles, the fi ndings may be translated to frozen cycles as well.…”

“…Recipient age, BMI, preexisting medical conditions, endometriosis, oocyte number, total motile sperm, ICSI, fertilization rate, number of 2PN zygotes, and the presence/absence of supernumerary embryos available for cryopreservation did not signi fi cantly affect a recipient's chance for pregnancy. More recently, Bodri et al studied 444 recipients (222 pairs) sharing oocytes from the same donor with discordant outcomes [ 6 ] . They studied recipient age, obstetrical (gravidity and parity) and gynecological variables (previous uterine surgery, uterine fi broids, uterine malformations, endometriosis, history of tubal infertility), previous oocyte donation cycles, duration of estrogen replacement, received cumulus-oocyte complexes, mature oocytes, fertilized oocytes, transferred embryo scores, mean embryo score, transfer dif fi culties, and semen parameters.…”