Prognostic factors for survival after salvage surgery for locoregional recurrence of colon cancer

Akiyoshi, Takashi; Fujimoto, Yoshiya; Konishi, Tsuyoshi; Kuroyanagi, Hiroya; Ueno, Masashi; Oya, Mototsugu; Miyata, Satoshi; Yamaguchi, Toshiharu

doi:10.1016/j.amjsurg.2010.03.003

Cited by 26 publications

(23 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A number of prognostic factors have been identified in patients with recurrent colonic cancer, including site of recurrence 9,13 , margin status 13 , number of sites of recurrence 9,13 , site of primary lesion 14 and size of recurrent tumour 7,13 . The present multivariable analysis identified a number of prognostically significant factors, including nodal involvement of primary disease, location of recurrence, subsite location of recurrence and vascular invasion of recurrent tumour.…”

Section: Discussionmentioning

confidence: 99%

Surgical resection of recurrent colonic cancer

Harji

Sagar

Boyle

et al. 2013

British Journal of Surgery

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Surgical resection of recurrent colonic cancer

Harji

Sagar

Boyle

et al. 2013

British Journal of Surgery

View full text Add to dashboard Cite

show abstract

“…3). Several studies revealed a clear survival advantage for patients who were eligible for surgery in the case of recurrent rectal carcinoma [60,61,62,63,64] as well as for colon carcinoma [65,66]. Although recurrence apart from N2 situations or adjacent organ invasion may be rarely expected in intraperitoneal colon carcinoma, a considerable number of cases may present in large-volume centers.…”

Section: Recurrent Diseasementioning

confidence: 99%

“…Nevertheless, complete resection remains the most important prognostic factor and should be the goal of treatment for locally recurrent CRC [63,65,66]. Multimodal and interdisciplinary treatment including neoadjuvant and adjuvant therapies should be discussed for all patients.…”

Section: Recurrent Diseasementioning

confidence: 99%

Surgery for Colorectal Cancer - Trends, Developments, and Future Perspectives

et al. 2016

View full text Add to dashboard Cite

Background: Although colorectal surgery is long established as the mainstay treatment for colon cancer, certain topics regarding technical fine-tuning to increase postsurgical recurrence-free survival have remained a matter of debate throughout the past years. These include complete mesocolic excision (CME), treatment strategies for metastatic disease, significance of hyperthermic intraperitoneal chemotherapy (HIPEC), and surgical techniques for the treatment of colorectal cancer recurrence. In addition, new surgical techniques have been introduced in oncologic colorectal surgery, and their potential to provide sufficiently radical resection has yet to be proven. Methods: A structured review of the literature was performed to identify the current state of the art with regard to the mentioned key issues in colorectal surgery. Results: This article provides a comprehensive review of the current literature addressing the above-mentioned current challenges in colorectal surgery. The focus lies on the impact of CME and, in relation to this, on lymph node dissection, as well as on treatment of metastatic disease including peritoneal spread, and finally on the treatment of recurrent disease. Conclusion: Uniformly, the current literature reveals that surgery aiming at complete malignancy elimination within multimodal treatment approaches represents the fundamental quantum leap for the achievement of long-term tumor-free survival.

show abstract

“…Наряду с этим, на отдаленные резуль-таты лечения существенно влияют местные рецидивы рака ободочной кишки, которые представляют собой одну из его распростра-ненных форм. По данным публикаций отече-ственных и зарубежных авторов последнего десятилетия, местные рецидивы опухоли диагностируются в различные сроки после операции у 6,4 % -40 % больных [2,8]. По-казатели 5-летней выживаемости, несмотря на сочетание хирургического лечения с при-менением лучевой и химиотерапии, у боль-ных с местными рецидивами рака ободочной кишки остаются неудовлетворительными и составляют, по данным разных авторов, 37 % -58 % [4,11].…”

Section: Introductionunclassified

Results of treatment of patients with local recurrence of colon cancer.

Шелыгин¹,

Ачкасов²,

Филон³

et al. 2015

Zlokač. opuholi

View full text Add to dashboard Cite

Результаты.Послеоперационные осложнения отмечены у 6 (9,8 %) из 61 пациента. Летальных исходов не было. Прослежена судьба 64 (90,1 %) пациентов, из них в настоящее время живы без признаков возврата заболевания 34 (53,1 %) больных. Проведена оценка эффективности внутрибрюшной химиотерапии. Повторные местные рециди-вы развились у 5 (14,3 %) из 35 прослеженных больных, которым проводилась внутрибрюшная химиотерапия, и у 6 (20,7 %) из 29 прослеженных пациентов, получивших только хирургическое лечение (р = 0,2). Отдаленные мета-стазы выявлены у 9 (25,7 %) больных и 5 (17,2 %) пациентов сравниваемых групп (р = 0,17), а канцероматоз брюшины в 1 (2,9 %) и 4 (13,8 %) случаях (р = 0,09). Безрецидивная 5-летняя выживаемость у больных, которым проводилась внутрибрюшная химиотерапия, составила 57,1 %, при изолированном хирургическом лечении -48,3 % (р = 0,15).Ключевые слова: местные рецидивы рака ободочной кишки, комбинированные операции, внутрибрюшная хи-миотерапия

show abstract

Prognostic factors for survival after salvage surgery for locoregional recurrence of colon cancer

Cited by 26 publications

References 23 publications

Surgical resection of recurrent colonic cancer

Surgical resection of recurrent colonic cancer

Surgery for Colorectal Cancer - Trends, Developments, and Future Perspectives

Results of treatment of patients with local recurrence of colon cancer.

Contact Info

Product

Resources

About