Prognostic Factors and Outcome in Askin-Rosai Tumor: A Review of 104 Patients

Laskar, Siddhartha; Nair, Chandrika N.; Mallik, Suman; Bahl, Gaurav; Pai, Sheila R; Shet, Tanuja; Gupta, Tejpal; Arora, Brijesh; Bakshi, Ashish; Pramesh, C S; Mistry, Rajesh C.; Qureshi, Sajid; Medhi, Seema; Jambhekar, Nirmala A.; Kurkure, Purna; Banavali, Shripad; Muckaden, Mary Ann

doi:10.1016/j.ijrobp.2009.10.039

Cited by 41 publications

(34 citation statements)

References 21 publications

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“…This is a rare disease in the pediatric group, and even rarer in adults. Caucasian ethnic group is clearly predominant [4]. It is presented as a painful wall mass, often associated with dyspnea, cough, weight loss, Horner’s syndrome, or regional lymphadenopathy.…”

Section: Discussionmentioning

confidence: 99%

Askin’s tumor: a case report and literature review

et al. 2013

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Askin’s tumor is a primitive neuroectodermal tumor developing from the soft tissues of the chest wall. Its diagnosis approach is complex and requires a multidisciplinary team. Given the rarity of this entity, no regimen has been validated in the literature. We report two cases of Askin’s tumor with a major response to polychemotherapy and surgical resection in one case. These cases show that treatment of Askin’s tumor should be multimodal, requiring discussion in multidisciplinary tumor working groups.

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Section: Discussionmentioning

confidence: 99%

Askin’s tumor: a case report and literature review

et al. 2013

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“…About 17% of malignant tumors of the chest are of the Ewing sarcoma family of tumors and 15% of all Ewing sarcomas are localized to the chest wall [ 14 , 18 ] . Ewing sarcoma may occur in any age group but the median age of presentation is 15 years.…”

Section: Pulmonary and Chest Wall Malignanciesmentioning

confidence: 99%

Malignant pulmonary and mediastinal tumors in children: differential diagnoses

McCarville¹

2010

Cancer Imaging

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Conventional chest radiography is the most common imaging procedure in children. When a chest mass is discovered, cross-sectional imaging is often required to accurately localize and characterize the lesion in order to narrow the differential diagnosis. Knowledge of the differential diagnostic possibilities for chest tumors in children is important for both the pediatric and general radiologist because they differ from adults. The more common pediatric, malignant, mediastinal and pulmonary tumors and the characteristic imaging and clinical features that are useful in distinguishing between them are discussed in this review.

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“…It mainly develops from the soft tissue of chest wall, predominantly in paravertebral region. These tumors are more common in Caucasian ethnic group [4]. A reciprocal translocation between chromosomes 11 and 22 in about 85% of tumors creates a chimeric EWS-FLL-1 fusion gene.…”

Section: Discussionmentioning

confidence: 99%

Chest Wall PNET Masquerading as Breast Lump: A Case Report with Diagnostic Challenge

Mishra¹,

Gandhi²,

Rastogi³

et al. 2020

JCR

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Background: Chest wall primitive neuroectodermal tumor (PNET) is a rare tumor necessitating a prompt diagnosis. Unfortunately, the diagnosis of this tumor can be extremely challenging and misdiagnosis is at times unavoidable. Case Report: Here we present one such rare case of chest wall PNET. Patient initially had complaints of pain and lump in the right breast. Contrast enhanced computed tomography (CECT) of thorax showed large mass with both intra-thoracic and extra-thoracic extension. Trucut biopsy from lump was suggestive of PNET on histopathology and immunohistochemistry. Later patient was treated with induction chemotherapy with alternating VAC/IE followed by right chest wall resection. Post-operative histopathology was suggestive of complete pathological response. 18 FDG PET-CT done subsequently was suggestive of complete metabolic response. Conclusion: Chest wall PNETs may mimic as breast lump, posing diagnostic dilemma. Multimodality treatment may yield excellent outcome as in our case.

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Prognostic Factors and Outcome in Askin-Rosai Tumor: A Review of 104 Patients

Cited by 41 publications

References 21 publications

Askin’s tumor: a case report and literature review

Askin’s tumor: a case report and literature review

Malignant pulmonary and mediastinal tumors in children: differential diagnoses

Chest Wall PNET Masquerading as Breast Lump: A Case Report with Diagnostic Challenge

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