Prognosis in Relation to Blood Pressure Variability

Kario, Kazuomi

doi:10.1161/hypertensionaha.115.04800

Cited by 75 publications

(56 citation statements)

References 42 publications

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“…However, some studies suggested that low-reactive BPV (such as blunted surge, nocturnal hypertension, orthostatic hypotension) is also a risk factor of cardiovascular disease, which is also associated with target organ lesions of hypertensive patients. Therefore, it is necessary to study hyporeactive BPV indices and explore its relationship with hypertensive atherosclerosis [16][17].…”

Section: Introductionmentioning

confidence: 99%

Relationship between carotid artery sclerosis and blood pressure variability in essential hypertension patients

Xianglin

Zhan

et al. 2018

Computers in Biology and Medicine

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Objectives: This study aimed to investigate the relationship between the presence of carotid arteriosclerosis (CAS) and blood pressure variability (BPV) in patients with essential hypertension. Methods:One hundred and forty four essential hypertension patients underwent ambulatory BP monitoring for 24 hours after hospitalization. Common BPV metrics were calculated. General clinical parameters, including age, gender, height, weight, history of coronary heart disease, stroke, diabetes, hypertension, smoking and drink, were recorded. Biochemical indices were obtained from a blood test. Carotid intima-media thickness (IMT) and carotid plaques were assessed to separate patients into a non-CAS group (IMT0.9 mm; n=82) and a CAS group (IMT>0.9 mm; n=62). BPV metrics and clinical parameters were analyzed and compared between the two groups.

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Section: Introductionmentioning

confidence: 99%

Relationship between carotid artery sclerosis and blood pressure variability in essential hypertension patients

Xianglin

Zhan

et al. 2018

Computers in Biology and Medicine

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“…[7][8][9][10][11][12][13][14][15][16][17] However, the degree to which variability improves the prediction of cardiovascular risk is controversial. [18][19][20] Previous studies have shown that nighttime BP is generally a better predictor of cardiovascular outcomes than daytime BP in patients with hypertension, and diminished nocturnal decline in BP is associated with or predictive of organ damage and cardiovascular events. [21][22][23][24][25][26] Only a few studies have analyzed whether different phenotypes on the hypertension spectrum such as normotension, white-coat hypertension, masked hypertension, and sustained hypertension are associated with BP variability independent of mean BP.…”

Section: Introductionmentioning

confidence: 99%

“…This is in line with several observational and longitudinal analyses demonstrating the superior value of nocturnal BP compared with daytime BP in predicting cardiovascular events and all-cause mortality. 19,24,43 Nocturnal BP at resting conditions is the minimum BP needed for adequate organ perfusion, and high BP at night could overload the cardiovascular system and lead to negative effects on the heart and vascular structures. 44 Mentally stressful situations have been associated with masked hypertension and high BP variability.…”

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Short-term variability and nocturnal decline in ambulatory blood pressure in normotension, white-coat hypertension, masked hypertension and sustained hypertension: a population-based study of older individuals in Spain

et al. 2017

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El acceso a la versión del editor puede requerir la suscripción del recurso Access to the published version may require subscription Three observer-measured home BPs and 24-hour ambulatory blood pressure monitoring (ABPM) were performed under standardized conditions. BP variability was defined as BP standard deviation and coefficient of variation. Differences in BP variability and nocturnal BP decrease between groups were adjusted for sociodemographic and clinical covariates using generalized linear models. Of the cohort, 21.7% had white-coat hypertension, 7.0% had masked hypertension, 21.4% had sustained hypertension, and 49.9% were normotensive. Twenty-four hour, daytime, and nighttime systolic BP standard deviations and coefficients of variation were significantly higher in subjects with white-coat hypertension than those with normotension (p<0.05) and were similar to subjects with sustained hypertension. In untreated subjects, 24-hour but not daytime or nighttime BP variability indexes were significantly higher in subjects with white-coat hypertension than in those with normotension (p<0.05). Percentage decrease in nocturnal systolic and diastolic BP was greatest in the white-coat hypertension group and lowest in the masked hypertension group in all patients and untreated patients (p<0.05). Lack of nocturnal decline in systolic blood pressure was observed in 70.2% of subjects with normotension, 57.8% of subjects with white-coat hypertension, 78.1% of subjects with masked hypertension, and 72.2% of subjects with sustained hypertension (p<0.001). In conclusion, 24-hour BP variability was higher in subjects with white-coat hypertension and blunted nocturnal BP decrease was observed more frequently in subjects with masked hypertension. These findings may help to explain the reports of increased cardiovascular risk in patients with white-coat hypertension and poor prognosis in those with masked hypertension, highlighting the importance of ABPM.

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“…The sleep-trough MS was higher in Japanese than in European hypertensive patients after adjusting for age and 24-hour mean BP levels (40. patterns characterizing the diurnal BP profile, among which an exaggerated sleep-trough morning surge (MS) of BP has been reported to predict cardiovascular events. [10][11][12][13] However, when considering the association between the sleep-trough MS and stroke, different results have been reported from the analysis of different data sets. In Japanese elderly hypertensive patients, a significant association between stroke and the degree of MS was found, 10 whereas this was not the case when an international ABPM database or a European ABPM database was analyzed.…”

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Ethnic Differences in the Degree of Morning Blood Pressure Surge and in Its Determinants Between Japanese and European Hypertensive Subjects

et al. 2015

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Prognosis in Relation to Blood Pressure Variability

Cited by 75 publications

References 42 publications

Relationship between carotid artery sclerosis and blood pressure variability in essential hypertension patients

Relationship between carotid artery sclerosis and blood pressure variability in essential hypertension patients

Short-term variability and nocturnal decline in ambulatory blood pressure in normotension, white-coat hypertension, masked hypertension and sustained hypertension: a population-based study of older individuals in Spain

Ethnic Differences in the Degree of Morning Blood Pressure Surge and in Its Determinants Between Japanese and European Hypertensive Subjects

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