Prognosis and prognostic factors in patients with hypertrophic cardiomyopathy in Japan: results from a nationwide study

Abstract

The nationwide survey of patients with hypertrophic cardiomyopathy yielded important information on its prognosis and prognostic factors. These observations afford, for the first time, a measure of risk stratification in patients with HCM in Japan.

Clinical Impact of Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy Results From Kochi RYOMA Study

“…Our regional cohort in the Kochi RYOMA study was older than HCM cohorts in previous studies, [7][8][9][10][11]18 probably because Kochi Prefecture, where our study was performed, is located far from urban areas and is one of the most aged communities in Japan. The percentage of male patients in our cohort (64%) was similar to the percentages in previous studies in Western countries and Japan.…”

“…The percentage of male patients in our cohort (64%) was similar to the percentages in previous studies in Western countries and Japan. [7][8][9][10][11]18 Although half of the patients were diagnosed because of symptoms, severe functional disability (NYHA class III/IV) was not common in our study. It is notable that embolic stroke was the first clinical manifestation leading to diagnosis of HCM in 6 patients (although ECG abnormalities had been detected in some of those patients, further evaluation had not been performed.).…”

Prognosis and Prognostic Factors in Patients With Idiopathic Dilated Cardiomyopathy in Japan Results From a Nationwide Study

“…A nationwide survey of the prognosis of idiopathic hypertrophic cardiomyopathy was performed at the same time. 15 Age Statistical Analyses Survival estimates were calculated using the Kaplan-Meier method, and the 5-year (1,825 days) survival probability was calculated for the overall cohort. Patients were classified on the basis of baseline prognostic factors.…”

Patients’ Characteristics and Clinical Course of Hypertrophic Cardiomyopathy in a Regional Japanese Cohort ― Results From Kochi RYOMA Study ―

“…4-10 However, there have been few studies of the clinical features of HCM in a prospectively assembled, community-based cohort in Japan. 11 Therefore, in 2004, we established the Kochi Cardiomyopathy Network, named the Kochi RYOMA (registry of myocardial diseases) study, to provide detailed information on the clinical features of HCM in an unselected regional Japanese population. 12 For the present study, we obtained follow-up data in order to assess the…”