Profile of Vitamin D in Patients Attending at Tertiary Care Hospital, Bangladesh

Abstract

Introduction: Vitamin D deficiency is a common condition prevalent among both developed and developing countries where it is seen mostly in females. It has been linked to various skeletal and non-skeletal diseases. This study was done to find out the distribution of Vitamin D deficiency attending the outpatient department of a tertiary care hospital. Methods: This descriptive cross-sectional study was done among the patients attending the outpatient department of a tertiary care hospital in Dhaka, Bangladesh. Methodology: The six months study was conducted from January 2019 to July 2019. The ethical approval was taken from the Institutional Review Committee of the institute where we conducted the study. Convenient sampling was done. The collected data was entered in Microsoft Excel and was analyzed in the Statistical Package for the Social Sciences (SPSS) version 23. Results: Out of 170 participants, the distribution of vitamin D deficiency was 24 (14.1%) and insufficient vitamin D in 59 (34.7%) of the patients. The mean serum vitamin D concentration by gender was 33.20±13.10ng/ml in males and 29.85±9.99 ng/ml in females. Mean age of deficient cases are 18.25±23.47 years and for sufficient cases mean age is 6.92±7.36 years. A total of 16 females and 8 males had vitamin D deficiency. Conclusions: Vitamin D deficiency was prevalent especially in girl child.

Vitamin D levels in patients attending a tertiary care hospital in Mogadishu, Somalia: a retrospective review of 28,125 cases

“…Globally, the female gender is one of the most important predictors of vitamin D deficiency 13,14 . The increased frequency seen in females was comparable with other studies in Saudi Arabia (78.1%) 10 , Libya (58.8%) 14 , Nepal (76.1%) 11 , and Bangladesh (46%) 17 . This finding was due to some factors that females predominate for vitamin D deficiency.…”

“…The observation of various reports of older people or increased ages that have lowered vitamin D serum concentration is because the older group might not be having vitamin D and calcium supplements or decreased dietary intake, diminished sunlight exposure, reduced skin thickness, impaired intestinal absorption, and impaired hydroxylation of vitamin D in liver and kidney [15][16][17] . Another necessary explanation is that those younger ages in this study have higher vitamin D levels than older ages where the MENA region (the Middle East/Africa) generally spends more time outdoors compared with other age groups with lower vitamin D levels 13,14,18 .…”

Status of Vitamin D among Patients Visiting a Tertiary Care Centre in Rupandehi, Nepal

“…Bhattarai et al in their study found 34.8% deficient, 35.9% insufficient, 28.7% normal and 0.6% hypervitaminosis D (Bhattarai et al, 2019). Sadiya et al had also conducted similar study in Bangladesh and found 14.1% deficient, 34.7% insufficient and 51.2% normal level of vitamin D (Sadiya et al, 2021). In a study conducted by Lee et al in 2008 found the prevalence of vitamin D deficiency as approximately 30-50% of the general population which was close to that of our study as 57.7% (Lee et al, 2008).…”

“…Vitamin D is one of the fat-soluble prohormones which has essential roles in the maintenance of various physiological processes (Sadiya et al, 2021). Maintenance of calcium and phosphate homeostasis is played by the essential role of vitamin D and these both minerals have important role for proper bone health (Renkema et al, 2008).…”