Abstract:Background: Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. Loss of pyramidal and anterior horn motor neurons leads to progressive limb weakness, disability, dysarthria, dysphagia and respiratory insufficiency with a progressive fatal course. Objective: To evaluate the epidemiological and clinical characteristics of amyotrophic lateral sclerosis (ALS) in the Republic of Moldova (3,559,497 inhabitants) during a 5-year period (2009)(2010)(2011)(2012)(2013). Materials and methods: To … Show more
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