Proficiency testing for HIV, tuberculosis and malaria diagnosis in clinical laboratories in Nigeria

Audu, Rosemary; Onubogu, Catherine; Okoye, Rosemary N.; Nwokoye, Nkiru N.; Onwuamah, Chika; Musa, Adesola Z.; Raheem, Toyosi; Aniedobe, Maureen; Nduaga, S.; Essien, Ini-Obong; Idigbe, Emmanuel O.

doi:10.4102/ajlm.v3i1.102

Cited by 7 publications

(8 citation statements)

References 13 publications

(19 reference statements)

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“…In this study the average PT performance the 6 PT events for 28 PT programs was 67.75% success rate even though significant improvement is not observed through the trend of PT event which among participated facilities those graded as ACC or UNACC which account 97507 (79.9%) among the total PT challenges distributed and the success rate or the rate of scoring ACC were 66.00%, 67.61%, 67.22%, 67.35%, 67.48% and 70.87% which showed relatively good performance compared to the study conducted among 12 government hospitals laboratories in Addis Ababa, who had been participated in proficiency tasting schemes for 20 clinical laboratories test parameters in 6 cycles from 2012 to 2013 G. C. in over 6 cycle showed that those meet the analytical performance score of 80 and above is 40.42%, 26.67%, 26.67%, 51.67%, 37.09%, 38.37% this indicates no improvement in quality through time [9]. This study was comparable with the study conducted in Nigeria between 2009 and 2011 [7]. Four rounds of pre-characterized plasma panels for HIV, sputum films for tuberculosis and blood films for malaria were distributed quarterly scores increased from 74% to 95% from the first round to the third round, but decreased in the fourth round for HIV PT and average scores increased from 42% in the first round to 78% in the second round; but a decrease to 34% was observed in the fourth round for Tuberculosis PT while Malaria PT performance was 2% at first, but average scores increased between the second and fourth rounds, culminating in a fourth-round score of 39% which showed low performance compared to the study conducted on quality assurance for point of care testing among different heath facilities [11].…”

Section: Performance Ratesupporting

confidence: 73%

Performance of International External Quality Assessment Scheme Participant Laboratories in Ethiopia (2016-2018)

Mekonnen¹,

Gurmessa²,

Kebede³

et al. 2020

AJLM

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Section: Performance Ratesupporting

confidence: 73%

Performance of International External Quality Assessment Scheme Participant Laboratories in Ethiopia (2016-2018)

Mekonnen¹,

Gurmessa²,

Kebede³

et al. 2020

AJLM

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“…The proficiency testing performance score for HIV serology was consistently at 100%. Improved PTP in HIV serology score from 74% to 94% in a survey involving 44 laboratories in four trails following staff mentoring have been reported in Nigeria [28]. For the other parameters there was sustained improvement over the study period.…”

Section: Discussionmentioning

confidence: 70%

Evaluation of Laboratory Performance with Quality Indicators in Infectious Disease Hospital, Kano, Nigeria

Jegede¹,

Mbah²,

Aminu³

et al. 2015

OJCD

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Background: In January 2010, the implementation of quality management systems toward WHO-AFRO laboratory accreditation commenced in the Antiretroviral Treatment Laboratory of the Infectious Disease Hospital, Kano, Nigeria. Quality improvement projects were instituted in 2011 in line with ISO 15189 requirements for accreditation of medical laboratory. In this study we evaluated the performance of the laboratory through some set of quality indicators (QI). Methodology: This was a retrospective study to evaluate laboratory QIs monitored from January 2011 to December 2013. The QIs were specimen rejection rate (SSR), turnaround time (TAT), proficiency testing performance (PTP) and client satisfaction survey (CSS). Data was collected into an excel file for analysis and percentage performance compared among years. SSR & TAT were evaluated with the Sigma scale. Results: A total of 7920 (2194 in 2011, 2715 in 2012, 3011 in 2013) specimens were received for testing. 22 (0.28%) specimens were rejected and 81 (1.02%) specimens' results were reported after the acceptable TAT, giving a Sigma level of 4.27 and 3.82 for SSR and TAT respectively. There was steady improvement in PTP: CD4+ from 67% in 2011 to 90% in 2013, hematology from 81% in 2012 to 83% in 2013, blood film reading 79% in 2011 to 83% in 2013 and chemistry from 90% in 2011 to 93% in 2013. HIV serology recorded 100% throughout. CSS increased from 59% in 2012 to 78% in 2013. However, there was no statistically significance difference reported for PTP and CSS over the years (P > 0.05). Conclusion: The study highlights the need to continuously evaluate QIs and calls for more effort to improve on PTP and focuses on understanding and improving on clients concerns.

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“…External quality control programmes available Existing external quality programmes for microbiology are scarce, expensive, and address mostly HIV, tuberculosis, and malaria 42,[81][82][83][84][85] Reference laboratories…”

Section: Clinical Decision Makingmentioning

confidence: 99%

Clinical bacteriology in low-resource settings: today's solutions

Ombelet

Ronat

Walsh

et al. 2018

The Lancet Infectious Diseases

137

159

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Low-resource settings are disproportionately burdened by infectious diseases and antimicrobial resistance. Good quality clinical bacteriology through a well functioning reference laboratory network is necessary for effective resistance control, but low-resource settings face infrastructural, technical, and behavioural challenges in the implementation of clinical bacteriology. In this Personal View, we explore what constitutes successful implementation of clinical bacteriology in low-resource settings and describe a framework for implementation that is suitable for general referral hospitals in low-income and middle-income countries with a moderate infrastructure. Most microbiological techniques and equipment are not developed for the specific needs of such settings. Pending the arrival of a new generation diagnostics for these settings, we suggest focus on improving, adapting, and implementing conventional, culture-based techniques. Priorities in low-resource settings include harmonised, quality assured, and tropicalised equipment, consumables, and techniques, and rationalised bacterial identification and testing for antimicrobial resistance. Diagnostics should be integrated into clinical care and patient management; clinically relevant specimens must be appropriately selected and prioritised. Open-access training materials and information management tools should be developed. Also important is the need for onsite validation and field adoption of diagnostics in low-resource settings, with considerable shortening of the time between development and implementation of diagnostics. We argue that the implementation of clinical bacteriology in low-resource settings improves patient management, provides valuable surveillance for local antibiotic treatment guidelines and national policies, and supports containment of antimicrobial resistance and the prevention and control of hospital-acquired infections.

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Proficiency testing for HIV, tuberculosis and malaria diagnosis in clinical laboratories in Nigeria

Cited by 7 publications

References 13 publications

Performance of International External Quality Assessment Scheme Participant Laboratories in Ethiopia (2016-2018)

Performance of International External Quality Assessment Scheme Participant Laboratories in Ethiopia (2016-2018)

Evaluation of Laboratory Performance with Quality Indicators in Infectious Disease Hospital, Kano, Nigeria

Clinical bacteriology in low-resource settings: today's solutions

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