Proficiency test on the determination of polyethylene and polybutylene terephthalate cyclic oligomers in a food simulant

Tsochatzis, Emmanouil D.; Lopes, Joao Alberto; Dehouck, Pieter; Robouch, P.; Hoekstra, Eddo J.

doi:10.1016/j.fpsl.2019.100441

Cited by 21 publications

(40 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The identification and quantification of the target substances migrating from the PP cups was performed using an ultra-high-pressure liquid chromatograph coupled to a quadrupole time-of-flight mass spectrometer (UHPLC-qTOF-MS) and an high-performance liquid chromatograph with fluorescence detection (HPLC-FLD) (Alberto Lopes, Tsochatzis, Emons, & Hoekstra, 2018; Tsochatzis et al, 2018).…”

Section: Methodsmentioning

confidence: 99%

“…The injection volume was 5 μL. Both methods have been previously single-laboratory validated by the EURL-FCM (Alberto Lopes et al, 2018; Tsochatzis et al, 2018).…”

Section: Methodsmentioning

confidence: 99%

“…The pre-heating of FCM prior to migration testing could be one way of maintaining the temperature in the migration test during the contact time within a predefined temperature range. Two inter-laboratory exercises (ILCs) (Tsochatzis, Mieth, Simoneau, & Hoekstra, 2016; Tsochatzis, Alberto Lopes, Robouch, & Hoekstra, 2018) were organised to assess the competence of National Reference Laboratories (NRLs) for FCMs in monitoring the migration of FCM No. 500 (2,5-bis(5-tert-butyl-2-benzoxazolyl)thiophene) from polypropylene (PP) food contact cups into official food simulant D1 (ethanol 50% v/v) (Regulation (EU) No 10/2011).…”

Section: Introductionmentioning

confidence: 99%

“…Unexpectedly some of the NRLs pre-heated the cups prior to migration testing. Principal component analysis of the results showed that pre-heating of the cups had increased the variance of the migration results (Tsochatzis et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Influence of pre-heating of food contact polypropylene cups on its physical structure and on the migration of additives

Lopes

Tsochatzis

Robouch

et al. 2019

Food Packaging and Shelf Life

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Methodsmentioning

confidence: 99%

“…The injection volume was 5 μL. Both methods have been previously single-laboratory validated by the EURL-FCM (Alberto Lopes et al, 2018; Tsochatzis et al, 2018).…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Influence of pre-heating of food contact polypropylene cups on its physical structure and on the migration of additives

Lopes

Tsochatzis

Robouch

et al. 2019

Food Packaging and Shelf Life

Self Cite

View full text Add to dashboard Cite

show abstract

“…10/2011 specifies the use of aqueous food simulants, there is a priori a high probability that hydrolysis reactions would occur during the migration test. This could be especially the case during migration at high temperatures which could accelerate the hydrolysis rate [ 25 , 26 ]. Therefore, the analysis of FCM No.…”

Section: Resultsmentioning

confidence: 99%

Development and validation of a multi-analyte GC-MS method for the determination of 84 substances from plastic food contact materials

et al. 2020

Self Cite

View full text Add to dashboard Cite

Chemical substances shall not migrate from food contact materials (FCM) at levels that are potentially harmful for the consumers. Each of the current analytical methods applied to verify the migration of substances from FCM covers only one or few substances. There is a very limited number of publications on the development of analytical methods allowing the simultaneous determination of several classes of FCM substances, and almost none of them reported methods entirely dedicated to the ones in the positive list of Commission Regulation (EU) No. 10/2011 for plastic FCMs. Therefore, a simple, sensitive and reliable multi-analyte method was developed for the analysis of FCM substances in food simulants. It employs an optimised liquid-liquid extraction with dichloromethane as extraction solvent in the presence of 10% m/v NaCl, followed by quantitative analysis with gas chromatography coupled to mass spectrometry (GC-MS). A combination of total ion chromatograms (TICs) and extracted ion chromatograms (EICs) was used. The optimisation and validation of the method have been carried out according to current international guidelines. Adequate sensitivity was demonstrated in the selected concentration ranges for most of the analytes, with limits of quantification (LOQs) at least three times lower than the legislative limit, when existing. The results showed that the method is sufficiently accurate for the majority of substances, with recoveries between 70 and 115% and relative standard deviations (RSDs) smaller than 20% at three concentration levels. The method was applied to the analysis of some FCM multilayers. The method allows, for the first time, the simultaneous quantification of 84 FCM substances in two of the official food simulants (A and C) at levels of a few ng g −1 . Graphical abstract Electronic supplementary material The online version of this article (10.1007/s00216-020-02758-7) contains supplementary material, which is available to authorized users.

show abstract

Liquid chromatography-mass spectrometry method for the determination of polyethylene terephthalate and polybutylene terephthalate cyclic oligomers in blood samples

et al. 2022

View full text Add to dashboard Cite

Proficiency test on the determination of polyethylene and polybutylene terephthalate cyclic oligomers in a food simulant

Cited by 21 publications

References 10 publications

Influence of pre-heating of food contact polypropylene cups on its physical structure and on the migration of additives

Influence of pre-heating of food contact polypropylene cups on its physical structure and on the migration of additives

Development and validation of a multi-analyte GC-MS method for the determination of 84 substances from plastic food contact materials

Liquid chromatography-mass spectrometry method for the determination of polyethylene terephthalate and polybutylene terephthalate cyclic oligomers in blood samples

Contact Info

Product

Resources

About