Prof. Dr. A. H. W. Aten, Jr.

Lindner, Liandro da Cruz

doi:10.1524/ract.1977.24.4.v

Cited by 6 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The separation of enantiomers is an important issue, especially in pharmaceutical analysis, because stereochemistry can have a significant effect on the biological activity of a drug, and the antipode of a chiral drug is regarded as one of its impurities. Therefore various kinds of analytical methods have been developed, high-performance liquid chromatography (HPLC) being the most widely used for the separation of enantiomers [6,7], because most drugs are involatile, polar or even ionic. In HPLC, one can use chiral stationary-phase columns, often commercially available, to develop the chiral separation method.…”

Section: Introductionmentioning

confidence: 99%

Enantiomeric separation of drugs by affinity electrokinetic chromatography using dextran sulfate

et al. 1994

View full text Add to dashboard Cite

Dextran sulfate (sodium salt), which is a mixture of a linear a-(1,6)-linked D-glucose polymer having a sulfate group in the molecule, has been employed as a chiral selector in affinity electrokinetic chromatography (EKC) for the separation of enantiomers of drugs. Enantiomers of trimetoquinol hydrochloride and its positional isomer have been successfully separated by the method using a 3-5% dextran sulfate buffer solution of pH 5.5 within 20 min. The effects of buffer pH, concentration of dextran sulfate, and additives (such as an organic solvent, urea and a surfactant) on the enantioselectivity were investigated. The choice of pH and the concentration of dextran sulfate has been important for the

show abstract

Section: Introductionmentioning

confidence: 99%

Enantiomeric separation of drugs by affinity electrokinetic chromatography using dextran sulfate

et al. 1994

View full text Add to dashboard Cite

show abstract

“…It appears that in Atherix, Spaniopis and h'ymphoromyia the blood-sucking habit is limited to females, and Lindner (1925) pointed out that female Atherix and Symphoromyia possess mandibles as do Tabanidae of the same sex. Becher (1882) stated that, although the males of these genera lack both mandibles and maxillae, yet there is no difference in their mode of life, and he suggested that both sexes may be predatory on small insects.…”

Section: Conclusion and Discussionmentioning

confidence: 99%

The mouth‐parts of the Down‐looker fly, Rhagio (=Leptis) scolopacea (L.) Diptera, Rhagionidae)

Bletchly¹,

Varley²

1955

Proceedings of the Zoological Society of London

View full text Add to dashboard Cite

Summary. A detailed account is given of the anatomy of the mouth‐parts of Rhagio scolopacea (L.) (Rhagionidae) and some comparisons made with earlier studies of Scopeuma stercoraria (L.) (Cordyluridae) and Empis livida (L.) (Empididae). The probable movements and functions of the mouth‐parts are deduced and the morphological adaptations to these discussed and compared in a similar manner. Rhagio shows no predatory adaptations and is possibly a nectar feeder. Homologies are traced including that of the maxilla and a general discussion on homology, with special relation to particular problems in these three species, is included.

show abstract

“…cellulose esters, helicity being responsible for the resolution. Attractive interactions and the inclusion of analyte in the chiral helix leads to enantioseparation (Lindner and Mannschreck, 1980). A fourth category of CSPs is ligand exchange phases, now commercially available, containing proline or hydroxy proline bound to silica via a spacer and then complexed with copper ion.…”

Section: )mentioning

confidence: 99%

Resolution of enantiomers of amino acids by HPLC

Bhushan¹,

Joshi²

1993

Biomedical Chromatography

View full text Add to dashboard Cite

Application of HPLC as a prime tool in the area of enantiomeric resolution has opened doors of success and varied interest. Use of chiral reagents either indirectly (as derivatization reagent) or directly (added to stationary or mobile phase) has led to achieve resolution of a wide range of compounds. Amino acids, being important molecules with simple structure and easy availability, have been extensively studied. A bibliographic survey on HPLC resolution of amino acids and derivatives along with a brief discussion on general methods of enantiomeric separation has been presented.

show abstract

Prof. Dr. A. H. W. Aten, Jr.

Cited by 6 publications

References 0 publications

Enantiomeric separation of drugs by affinity electrokinetic chromatography using dextran sulfate

Enantiomeric separation of drugs by affinity electrokinetic chromatography using dextran sulfate

The mouth‐parts of the Down‐looker fly, Rhagio (=Leptis) scolopacea (L.) Diptera, Rhagionidae)

Resolution of enantiomers of amino acids by HPLC

Contact Info

Product

Resources

About